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Mu Tong (Caulis Mutong)
Mu Tong or Bai Mu Tong or Chuan Mu Tong is also known as akebia caulis. The bitter and cool herb has been used in TCM to treat Promotes urinate, promotes lactation, for treatment of urinary tract infection, edema. pain in the joints, low grade fever with achiness, cold feet, etc., as it calms pain on urination, clears Heat, etc., by enhancing the function of bladder, heart and small intestine channels.
Ingredients(1)
1. Aristolochic acid I
2. Aristolochic acid II
3. Aristolochic acid III
4. Aristolochic acid III a
5. Aristolochic acid VII a
6. Aristolactam I
7. Aristolactam II
8. Aristolactam III a
9. Etc.
Health Benefits
1. Aristoloside
Aristoloside, an extract of Guan-mu-tong (Gmt; Caulis aristolochiae manshuriensis) showing a marked anticancer potential. In the treatment of The treatment induced the inhibition of preneoplastic mammary gland growth and the stimulation of the excretion of urinary component. Ovarian follicles were dominant and the oestrous stage was elongated by the treatment. Aristoloside had little affect on normal mammary gland growth and serum levels of prolactin and free fatty acid. All findings were in agreement with those obtained from studies on chronic treatment with Gmt, and aristoloside is thus strongly suggested as being one of the major components of Gmt(2).
2. Lactation
Gmt improved pup growth rate and mammary DNA content. No pups were lost during the experiment. Similar results were obtained by 0.5% Xia-ru-yong-quan-tang (Xryqt), a Chinese herbal medicine, which contained 0.05% Gmt. Xryqt further prevented a decline in ovarian weight seen by 0.05% Gmt treatment and significantly increased mother weight(3).
3. Antipsychotics effects
In this retrospective, cross-sectional study, 1795 patients with schizophrenia who were randomly selected from 17 psychiatric hospitals in China were interviewed face-to-face using a structured questionnaire. Association analyses were conducted to examine correlates between Chinese medicine (CM) use and demographic, clinical variables, antipsychotic medication mode, and clinical outcomes. The prevalence of concomitant CM and antipsychotic treatment was 36.4% [95% confidence interval (95% CI) 34.2%-38.6%]. Patients using concomitant CM had a significantly greater chance of improved outcomes than non-CM use (61.1% vs. 34.3%, OR = 3.44, 95% CI 2.80-4.24). However, a small but significant number of patients treated concomitantly with CM had a greater risk of developing worse outcomes (7.2% vs. 4.4%, OR = 2.06, 95% CI 2.06-4.83)(4).
4. Antinociceptive and anti-inflammatory effects
Treatments with 10 and 30 mg/kg perorally of these two sapogenins obtained the methanol (MeOH) extract from A. quinata stems and fractionated this extract into CHCl(3), butanol (BuOH), and H(2)O fractions. produced significant antinociceptive/ anti-inflammatory effects in the rat, suggesting that the sapogenins may act as resultant active compounds. Compounds 2 and 3 inhibited dye leakage into the peritoneal cavity induced by acetic acid, and the latter was more active than the former. The anti-inflammtory effects were further supported by the reduction of carrageenan-induced lipid peroxidation and hydroxy radical content in serum. These results suggest that the antinociceptive/anti-inflammatory properties of the stem of A. quinata can be attributed to the sapogenins oleanolic acid and hederagenin(5).
5. Etc.
Side Effects
1. Do not use in case of diseases without damp heat, qi and fluid deficiency
2. Do not use the herb in newborn. children or if you are pregnant or breast feeding without forst consulting with the related field specialist.
3. The herb can cause unexpected severe adverse reactions(a)
4. Etc.
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(a) http://www.ncbi.nlm.nih.gov/pubmed/9536471
(1) http://www.ncbi.nlm.nih.gov/pubmed/21213538
(2) http://www.ncbi.nlm.nih.gov/pubmed/9066658
(3) http://www.ncbi.nlm.nih.gov/pubmed/7572777
(4) http://www.ncbi.nlm.nih.gov/pubmed/21359185
(5) http://www.ncbi.nlm.nih.gov/pubmed/15857214
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