Scientists may have found a natural remedy for the treatment of irritable bowel syndrome with no side effects, according to studies.
Irritable bowel syndrome is a condition characterized by abdominal pain or discomfort, bloating, and alteration of bowel habits at least three times a month for the last 3 months without preexistence of other diseases.
According to the statistic, IBS affects approximately over 11% of the population globally and only 30% of these patients consult physicians for their IBS symptoms. People with IBS without seeing their doctors were found to experience a significantly reduced quality of life and psychological symptoms.
Compared to the male counterpart, women are at high risk of the condition. Believe or not there is 25% less IBS diagnosed in the population of over 50 years of age.
People with family history and the genetic factors are at a higher risk of the condition onset and most patients diagnosed with IBS are found infected by other functional disease compared to the general population.
Besides family history, gender, and genetic factors, other most common risk factors of IBS include smoking, frequent alcohol consumption, younger age, according to epidemiological studies.
Some researchers suggested that a sedentary lifestyle, a type of lifestyle involving little or no physical activity is also a major component in the Western world associated with IBS.
By examing the attenuation of gravitational aid to distal intestinal motility, resulting in damaging chronic intestinal distention, researchers at the McGill Centre for Studies in Aging, the prevalence of IBS irritable bowel syndrome have worsened in recent years owing to excessive dietary fiber intake.
Dr. said, "Potential solutions include augmenting weight-bearing time, moderating dietary fiber consumption, stimulating distal colon evacuation through chemical means and developing pharmaceuticals to block the reflexive distal colon distention associated with fiber consumption".
And, " Amplified intestinal distention commenced when all classes of Renaissance Europeans became the first group in human history to wear shoes, which led to a sedentary lifestyle that moderates gravitational aid to colon motility and evacuation".
Therefore, by engaging in daily moderate exercise and following a healthy diet, not only can prevent the syndrome but also treat IBS. Please consult with your dietitian for a better diet management that is suitable for you.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.
Herbal medicine has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
With an aim to find a natural compound or remedy for the prevention and treatment of irritable bowel syndrome (IBS), researchers investigated the beneficial effects of a mixture of Aloe vera (AV) and Matricaria recutita (German chamomile, GC) in an experimental model.
IBS-induced rats by a 5-day divided to the groups of control (water), GC (300 mg/kg), loperamide (10 mg/kg), mixed AV and GC (50: 50 at doses of 150, 300 or 450 mg/kg assigned as Mix-150, Mix-300 and Mix-450, respectively).
The application of mixed AV and GC showed a significant reduction of pro-inflammatory cytokines and oxidative stress markers in the IBS-induced rats.
Futhermore, lipid peroxidation (LPO) in colonic cells was also decreased substantially in the mixture treatment group, compared to in the control group.
Moreover, GC inhibited only small bowel transit while the AV/GC mixture delayed gastric emptying at the doses of 150 and 300 mg/kg, compared to that of the AV/GC mixture which reduces colonic transit and small bowel transit at the dose of 150 mg/kg.
Dr. Asadi-Shahmirzadi A and colleagues at the final day of the experiment said, "The severity of stress-induced IBS was diminished by the AV/GC mixture at all doses used but not dose-dependently, via inhibiting colonic MPO activity and improving oxidative stress status".
In order to understand the additional effects of Aloe vera in the treatment of IBS, researchers examined the efficacy of AV on IBS in refractory secondary care patients.
Patients with IBS )with 58 patients randomized, 49 completed the protocol to 1 month and 41 to 3 months) were randomized to receive AV or matching placebo for a month.
Symptoms were assessed at baseline, 1 and 3 months.
Aloe vera treatment group showed a significant effect in diarrhea at 1 month. There is a possibility that improvement occurred in patients with diarrhea or alternating IBS whilst taking AV.
The findings suggested that Aloe vera used alone or combined with chamomile for the prevention and combined with the primary medicine for the treatment of irritable bowel syndrome (IBS), pending to the results of large sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Benefit of Aloe vera and Matricaria recutita mixture in rat irritable bowel syndrome: Combination of antioxidant and spasmolytic effects by Asadi-Shahmirzadi A, Mozaffari S, Sanei Y, Baeeri M, Hajiaghaee R, Monsef-Esfahani HR, Abdollahi M.(PubMed)
(2) Randomised double-blind placebo-controlled trial of aloe vera for irritable bowel syndrome.
Davis K, Philpott S, Kumar D, Mendall M.(PubMed)
(3) The epidemiology of irritable bowel syndrome by Caroline Canavan, Joe West, and Timothy Card. (PMC)
(4) A common cause of irritable bowel syndrome and diverticulitis: chronic distal colon distention from sedentary behavior and excessive dietary fiber by Robbins SE. (PubMed)
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