Herbal Burdock may have a potential effect in the protection of your gastrointestinal tract against the
Gastroprotective activity is an action which maintains the function of the digestive system against pathogens in the induction of gastric lesions.
The digestive system including the gastrointestinal (GI) tract, the liver, pancreas, and gallbladder process the function to digest foods and transfer the nutrients and fluids to the body's needs.
There is no single cause of the gastrointestinal disorder. Researchers suggested that the cause of the disorder can be attributed directly to the digestive system, or other systemic problems that facilitate the onset of disease.
However, according to the epidemiological studies, bacterial infection, viral infection, inflammation, muscle dysfunction, gallstones, stress, and intake of certain anti-inflammatory drugs are associated with the onset of the acute and chronic digestive disorders.
Dietary factors also play an important in the reduction and promotion of digestive dysfunction. people who are overeating, eating too much fatty food, not consuming enough fiber, and consuming too much alcohol and smoking are at a higher risk of digestive diseases, including ulcers and gastric acid reflux.
Dr. Linda Lee, M.D. in the article "5 Foods to Improve Your Digestion" posted on the John Hopkins Medicine shares five foods that promote healthier digestion and help you avoid common gastrointestinal symptoms, including whole grain, leafy green, lean protein, low fructose fruits, and avocado.
These results suggested if you are following a healthy diet with less saturated and trans fat, red meat and processed foods and increased intake of fruit and vegetables, you may be free of gastrointestinal disorders.
Dr. Hyams JS at the University of Connecticut School of Medicine and Division of Digestive Diseases and Nutrition in the study "Diet and gastrointestinal disease" said, "Dietary manipulation can be an important part of therapy for several common gastrointestinal disorders" and " In chronic nonspecific diarrhea and functional constipation, the provision of appropriate amounts of fiber and fluids may ameliorate symptoms. A thorough understanding of the role of diet is essential to the management of these disorders".
Burdock is a plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro.
The herb has been used thousands of years in Chinese and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.
In the study to reaffirm the traditional medicine use of herbal burdock for the treatment of digestive disorders, researchers at the State University of Campinas conducted an evaluation to examine the anti-ulcerogenic activity of the sesquiterpene onopordopicrin (ONP)-enriched fraction (termed the ONP fraction), obtained from burdock leaves.
In vivo models in rodents, mimicking this disease in humans. injection of ONP fraction (50 mg/kg, p.o.) significantly inhibited the mucosal injury induced by ethanol/HCl solution by 75%, indomethacin/bethanechol by 68.9%, and stress by 58.3% compared to nontreatment groups.
ONP fraction application also significantly increased serum somatostatin levels (82.1±4.1 vs. control group 12.7±4 pmol/L) and decreased serum gastrin levels (62.6±6.04 vs. control group 361.5±8.2 μU/mL) without alternating the altered the mucus production.
Further analysis found that gastrointestinal protection is attributed to the endogenous sulfhydryls in the ONP fraction.
Dr.de Almeida AB, at the final report, wrote, "antisecretory mechanism involved with the antiulcerogenic effect of the ONP fraction.
Additionally, in the study to evaluate the efficacy and the possible mechanisms involved in the gastroprotective effects of a chloroform extract (CE) of the roots from A. lappa and its fractions.conducted by the Universidade Federal do Paraná, researchers found that
* Oral pretreatment with CE (10, 30 and 100 mg kg(-1)) significantly reduced gastric lesions induced by ethanol by 61%, 70%, and 76%, respectively.
*Oral administration of CE (100 mg kg(-1) per day for 7 days) reduced the chronic gastric ulceration induced by acetic acid by 52%. Intraduodenal CE (100, 300 and 600 mg kg(-1)) reduced the total acidity of gastric secretion by 22%, 22% and 33%, respectively,
* Oral administration (10, 30 and 100 mg kg(-1)) inhibited total acidity by 50%, 60% and 67%, respectively.
These results reaffirm the study of the State University of Campinas that Herbal Burdock processes a significantly gastroprotective effect.
Dr. Dos Santos AC, the lead author after taking into account of con and confounder said, " the CE protects animals from gastric lesions by reducing gastric acid secretion via inhibition of gastric H+, K+ -ATPase."
Taken all together, Herbal Burdock processed bioactive ONP fraction and its chloroform extract (CE) may be considered functional food for the prevention and combines with the conventional medicine for treatment for gastrointestinal diseases.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Anti-ulcerogenic mechanisms of the sesquiterpene lactone onopordopicrin-enriched fraction from Arctium lappa L. (Asteraceae): the role of somatostatin, gastrin, and endogenous sulfhydryls and nitric oxide by de Almeida AB, Luiz-Ferreira A, Cola M, Di Pietro Magri L, Batista LM, de Paiva JA, Trigo JR, Souza-Brito AR. (PubMed)
(2) Gastroprotective activity of the chloroform extract of the roots from Arctium lappa L by Dos Santos AC, Baggio CH, Freitas CS, Lepieszynski J, Mayer B, Twardowschy A, Missau FC, dos Santos EP, Pizzolatti MG, Marques MC. (PubMed)
(3) Diet and gastrointestinal disease by Hyams JS(PubMed)
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