Friday, December 11, 2015

The Smoothie of avocado, Almond and green tea for prevention and treatment of Hyperlipidemia(High blood Cholesterol)

Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for people with High blood Cholesterol and high risk of the syndrome

Yield: 2 serving (about 8 ounce each)
1/2 cup avocado of any kind with seeds
1 cup almonds
1 cup green tea drink 1 cup green tea drink (Make from 4 grams(2 tea bags) of green tea, a slice of ginger and a cup of hot water lipped for 5 minutes, and set aside for cooling to room temperature)

1. Place the avocado, almonds, green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The findings of natural sources for reduced risk and treatment have been extremely difficult as many the found ingredients with potential values can not retain the same effectiveness through the large scale and multi center studies, probably due to physical differences in testing subjects.
Recent studies suggested that avocado, coconut meat and green tea may consist a therapeutic values used combination for reduced risk and treatment of high blood cholesterol. 

Avocados are a commercially valuable fruit and are cultivated in tropical climates throughout the world. It is a green-skinned, pear-shaped fruit that ripens after harvesting and native to the Caribbean, Mexico, South America and Central America.

According to the Bharathi Women's College, avocado process various health benefits including body weight reduction and lower blood cholesterol, through its modulating effect on endogenous fat synthesis and adiponectin((in regulating glucose levels as well as fatty acid breakdown)) formation through gene FGF21 a key mediator of fatty acid oxidation and lipid metabolism(1)

Dr. Padmanabhan M, and Dr. Arumugam G. said, " (The)hydro-alcoholic fruit extract of P. americana (HAEPA),.... exhibits hypolipidemic activity through increased expression of adiponectin (in regulating glucose levels as well as fatty acid breakdown) and PPAR-γ , a free fatty acids receptor " in animal model(2).

Furthermore, its leaf extracts in rat study, due to exhibit the reduced plasma glucose and influenced lipid metabolism mechanism are suggested to be use as a potential prevention against the development of atherosclerosis(3).
In support to above claims, the Instituto Politécnico Nacional showed that administration of avocado seed flour (ASF) significantly reduced the levels of total cholesterol, LDL-C, and prediction of the atherogenic index(4).

Almond consists of an outer hull and a hard shell with the seed (nut) inside is native to the Middle East. It is most widely cultivated seed in the world for it economic and health benefit.

Because of its significant impact on cardiovascular diseases, the exploration of almond has drawn attention of science community for its other potential mechanisms in human health.

 Dr. Jamshed H. and Dr., Gilani AH. said, "almond supplementation significantly prevented hyperlipidemia in all tested models. Supplementation suppressed cholesterol synthesis,... (through inhibition of activation of cholesterol formation in the liver)"(5).

According to the joint study lead by the University of Kansas School of Pharmacy, administration of dietary supplementation with almonds has shown decreases in low-density lipoprotein cholesterol (LDL-C), in does-dependent manner(6).

In a randomized, controlled, crossover study on the total of 20 mildly hypercholesterolemic subjects, intake of almonds of mildly hypercholesterolemic subjects improved serum lipid parameters, including low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol(7).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate.

Drinking green tea daily is found to associated to modulate lipid metabolism in hyperlipidemia  through reduction of hyperlipidemia and fat storage in the liver and heart of rats consumed sucrose-rich diet(8), as well as increased activity of antioxidant enzyme SOD in hypolipidemic effects(9), in comparison of black and green tea.

Other study by First Hospital of China Medical University of combination of Bamboo Leaf Flavones and Tea Polyphenols suggested that a high dose of bamboo leaf flavones (75 mg/kg/d) combined with a medium dose of teapolyphenols (500 mg/kg/d) exhibited optimal lipid-lowering effect and may be used as a natural lipid-lowering agent(10).

People who are at increased riskof Hyperlipidemia(High blood Cholesterol) due to family history and obesity.....should drink at least one cup daily and people with chronic Hyperlipidemia should drink the juices at least 3 times a day, depending to digestive toleration.
Change of life style and diet pattern as well as lose weight in over weight and obese subjects  are also recommended.

(1) The modulating effect of Persea americana fruit extract on the level of expression of fatty acid synthase complex, lipoprotein lipase, fibroblast growth factor-21 and leptin--A biochemical study in rats subjected to experimentalhyperlipidemia and obesity by Monika P1, Geetha A2.(PubMed)
(2) Effect of Persea americana (avocado) fruit extract on the level of expression of adiponectin and PPAR-γ in rats subjected to experimental hyperlipidemia and obesity by Padmanabhan M, Arumugam G.(PubMed)
(3) Hypoglycemic and hypocholesterolemic potential of Persea americana leaf extracts by Brai BI1, Odetola AA, Agomo PU.(PubMed)
(4) Hypolipidemic effect of avocado (Persea americana Mill) seed in a hypercholesterolemic mouse model by Pahua-Ramos ME1, Ortiz-Moreno A, Chamorro-Cevallos G, Hernández-Navarro MD, Garduño-Siciliano L, Necoechea-Mondragón H, Hernández-Ortega M.(PubMed)
(5) Almonds inhibit dyslipidemia and vascular dysfunction in rats through multiple pathways by Jamshed H1, Gilani AH2.(PubMed)
(6) Statins and almonds to lower lipoproteins (the STALL Study). by Ruisinger JF1, Gibson CA2, Backes JM3, Smith BK4, Sullivan DK5, Moriarty PM6, Kris-Etherton P7.(PubMed)
(7) Baru almond improves lipid profile in mildly hypercholesterolemic subjects: a randomized, controlled, crossover study by Bento AP1, Cominetti C1, Simões Filho A2, Naves MM3.(PubMed)
(8) Green, oolong and black tea extracts modulate lipid metabolism in hyperlipidemia rats fed high-sucrose diet by Yang M1, Wang C, Chen H.(PubMed)
(9) Comparative studies on the hypolipidemic and growth suppressive effects of oolong, black, pu-erh, and greentea leaves in rats by Kuo KL1, Weng MS, Chiang CT, Tsai YJ, Lin-Shiau SY, Lin JK.(PubMed)
(10) Bamboo Leaf Flavones and Tea Polyphenols Show a Lipid-lowering Effect in a Rat Model of Hyperlipidemia by Yang C1, Yifan L1, Dan L2, Qian Y3, Ming-Yan J1.(PubMed)

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