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Tuesday, December 15, 2015

The tasty Smoothie for prevention and treatment of Metabolic syndrome

Kyle J. Norton(Scholar)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


The smoothie for people with increased risk and treatment of Metabolic syndrome
Yield: 2 serving (about 8 ounce each)
1 cup carrot
1/2 cup red cabbage
1 cup green tea drink (Make from 4 grams of green tea, and a cup of hot water lipped for 5 minutes, and let cool to room temperature)


1. Place the red cabbage, carrot, and green tea, in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The dream of finding the natural resource for treatment of age-related chronic inflammatory disease
such as metabolic syndrome has been extremely difficult, probably due to the potent ingredient found effectively in animal levels can not induce the similar potential in human trials.
But some researchers suggested that plant-derived dietary phytochemicals and macro- and micronutrients with potential in modulated oxidative stress and inflammatory signaling and regulate metabolic pathways may be induced stable gene expression, epigenomically(1).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years used in traditional Chinese medicine for treatment of various diseases, including cancers and heart diseases.

Daily consumption of green tea has shown to reduce body weight and alleviate metabolic syndrome through  decreased glucose uptake s and fatty acid synthesis(2).

Green tea catechin, particularly its derivative (-)-epigallocatechin-3-gallate (EGCG) in number of human studies showed to protective effects on parameters related to the MetS(3). Dr, Wolfram Ssaid," there are numerous in vivo studies demonstrating that green tea and EGCG exert cardiovascular and metabolic benefits in these model systems" and "To prove the effectiveness for disease prevention or treatment, several multi-center, long-term clinical studies investigating the effects of one precisely-defined green tea product on cardiovascular and metabolic endpoints would be necessary"(4).

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The vegetable has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

Cyanidin 3-glucoside found in red cabbage showed to reverse the cardiovascular, liver and metabolic signs through ots effects in reduced impaired glucose tolerance, hypertension, cardiovascular remodelling, increased collagen deposition,....according to the joint study lead by the Victoria University(5).

Carrot can grow to 3ft tall. It is root vegetable with orange color normally, a sub spices of Daucus carota, belongs to the family Apiaceae, native to Asian and Europe.

Anthocyanins, phenolic acids and carotenoids found in purple carrots showed to improve dyslipidaemia, glucose tolerance, hypertension and insulin resistance as well as exerting CVD protective effects against against oxidative stress(6).

According to the University of Parma, epidemiological studies, anthocyanins exhibited anti inflammatory-related diseases, including metabolic syndrome through modulation of cell redox status and inhibition of pro inflammatory signaling pathways(7).
Chronic consumption of total polyphenol intake, including phenolic acids, in a population-based cross-sectional study of 2618 adults, aged 19 to 84 years, is found to associated to lower incidence of Metabolic syndrome, DR. Sohrab G and the research team at the Shahid Beheshti University of Medical Sciences insisted(8).

Carotenoids, another phytochemicals in carrot showed to associate to reduce risk of metabolic syndrome. In a study of 10-year period with 910 subjects (295 men and 615 women), lower serum β-carotene ius found in subjects with metabolic syndrome and eating a diet rich in carotenoids might help prevent the development of the MetS and its complications(9).
Furthermore, in support to above claim, the University of Queensland study also showed that low concentrations of serum alpha-, beta-carotenes and the sum of five carotenoids appear to be associated with metabolic syndrome status, according to the International Diabetes Federation 2005 criteria, collected from 1523 adults aged 25 years(10).

People who are at increased risk of Metabolic syndrome due to family history, gene mutation or obesity.....should drink at least one cup daily and people with Metabolic syndrome should drink the smoothie as much as they can, depending to digestive toleration  and liver acceptance.
Change of life style and diet pattern are also recommended.

References
(1) From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition? by Szarc vel Szic K1, Declerck K1, Vidaković M2, Vanden Berghe W1.(PubMed)
(2) Mechanisms of body weight reduction and metabolic syndrome alleviation by tea by Yang CS1,2, Zhang J3,2, Zhang L1,2, Huang J3,2, Wang Y3,2.(PubMed)
(3) The potential role of green tea catechins in the prevention of the metabolic syndrome - a review by Thielecke F1, Boschmann M.(PubMed)
(4) Effects of green tea and EGCG on cardiovascular and metabolic health by Wolfram S1.(PubMed)
(5) Cyanidin 3-glucoside improves diet-induced metabolic syndrome in rats by Bhaswant M1, Fanning K2, Netzel M3, Mathai ML4, Panchal SK5, Brown L6.(PubMed)
(6) Comparison of purple carrot juice and β-carotene in a high-carbohydrate, high-fat diet-fed rat model of themetabolic syndrome by Poudyal H1, Panchal S, Brown L.(PubMed)
(7) Flavan-3-ols, anthocyanins, and inflammation by Mena P1, Domínguez-Perles R, Gironés-Vilaplana A, Baenas N, García-Viguera C, Villaño D.(PubMed)
(8) Dietary polyphenols and metabolic syndrome among Iranian adults by Sohrab G1, Hosseinpour-Niazi S, Hejazi J, Yuzbashian E, Mirmiran P, Azizi F.(PubMed)
(9) High serum carotenoids associated with lower risk for the metabolic syndrome and its components among Japanese subjects: Mikkabi cohort study by Sugiura M1, Nakamura M2, Ogawa K1, Ikoma Y1, Yano M1.(PubMed)
(10) Metabolic syndrome and serum carotenoids: findings of a cross-sectional study in Queensland, Australia by Coyne T1, Ibiebele TI, Baade PD, McClintock CS, Shaw JE.(PubMed)

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