Tuesday, January 12, 2016

Most Common Diseases of elder: Respiratory Disease: Asthma Treatment: The Important Vitamin K

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease
 is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.


Asthma is a chronic inflammatory disease affecting the air way of the lung with recurring symptoms, such as wheezing, chest tightness, shortness of breath, and coughing. The disease affects people of all ages, and mostly starts during childhood. In the study of 463,801 children aged 13-14 years in 155 collaborating centres in 56 countries. Children self-reported, through one-page questionnaires, symptoms of these three atopic disorders. In 99 centres in 42 countries, a video asthma questionnaire was also used for 304,796 children, found that for asthma symptoms, the highest 12-month prevalences were from centres in the UK, Australia, New Zealand, and Republic of Ireland, followed by most centres in North, Central, and South America; the lowest prevalences were from centres in several Eastern European countries, Indonesia, Greece, China, Taiwan, Uzbekistan, India, and Ethiopia(1). In the United States, approximately, asthma affects 25 million people, 7 million of them are children.

                   The Effectiveness of Vitamin K

Vitamin K(K1, phylloquinone; K2, menaquinones), is a fat soluble vitamin, found abundantly in leafy green vegetables, broccoli, and Brussels sprouts, etc. It is best known for promotion of coagulation and bone health.
Epidemiological studies focusing vitamin K in reduced risk and treatment of asthma have been inconclusive(a)(b)(c).

Menaquinone (vitamin K2), a variant of vitamin K, in a double blind study of 191 patients with bronchial asthma, showed an effective rate of 90.9% in mild patients, 86.7% in moderate patients, and 72.7% in severe patients(1). Other researchers suggested that treatment of menaquinone for long periods in patients with bronchial asthma indicated a significant inhibition of the disease(2). The data base of PubMed showed limitation in quantity of the research, we, therefore make no conclusion of the effectiveness of the vitamin in reduced risk and treatment of asthma. Overdoses can induce symptoms of Skin rash, Diarrhea, Nausea, Vomiting, Anemia, etc. Please make sure you follow the guideline of the Institute of Medicine of the National Academies.

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(a) Maternal intake of vitamins A, E and K in pregnancy and child allergic disease: a longitudinal study from the Danish National Birth Cohort by Maslova E, Hansen S, Strøm M, Halldorsson TI, Olsen SF.(PubMed)
(b) Fat-soluble vitamins and atopic disease: what is the evidence? by Litonjua AA.(PubMed)
(c) [Antioxidant and fat intake in patients with polinic asthma].[Article in Spanish] by de Luis DA1, Izaola O, Aller R, Armentia A, Cuéllar L.(PubMed)
(1) Menaquinone (vitamin K2) therapy for bronchial asthma. II. Clinical effect of menaquinone on bronchial asthma by Kimur I, Tanizaki Y, Sato S, Saito K, Takahashi K.(PubMed)
(2) Menaquinone (vitamin K2) therapy for bronchial asthma. I. Mechanism of action menaquinone on allergic reactions by Kimura I, Tanizaki Y, Sato S, Saito K, Takahashi K.(PubMed)

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