Friday, January 29, 2016

The Curable Smoothie of Tomato and Almond Milk for Reduced Risk and Treatment of Alopecia areata

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Reduced Risk and Treatment of Alopecia Areata 

Yield: 2 serving (about 8 ounce each)
1 3/4 cup tomatoes
1 cup almond milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of alopecia areata has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Alopecia areata is a auto immune skin disease due to genetic mutation in which the immune system attacked the hair follicle, affecting unpredictable hair loss.
Strong evidences of number of renowned institutions suggested that natural sources, including carotenoids from tomatoes(3), and vitamin E from almond(7) may be a combination ingredients for reduced risk and treatment of alopecia areata(1) through their effects in influence in the reduction of  oxidative stress(1)(2) various pathways.

Tomato is a red, edible fruit, genus Solanum, belongs to family Solanaceae, native to South America. Because of its health benefits, tomato is grown world wide for commercial purpose
and often in green house.
Carotenoids, a major chemical compound found in tomato, in animal model, may be used for unraveling the pathogenesis of AA including the role of retinoic acid metabolism in the severity of disease and hair shaft proteins(3) and treatment of Alopecia areata(6). 
The Ohio State University study reveal the important of genes related retinoic acid (RA) synthesis causes of alopecia areata, and suggested that increased intake of vitamin A may reduce the cytokines and chemokines involved the hair loss progression(5).
Dr. Holler PD and Dr. Cotsarelis G. said," Hypovitaminosis A from inadequate vitA intake causes hair loss" and "dietary vitA may have a role in precipitating and maintaining alopecias as well"(4).

Almond consists of an outer hull and a hard shell with the seed (nut) inside is native to the Middle East and widely cultivated seed in the world for it economic and health benefit. According to Cairo University, vitamin E found abundantly in almond exhibited anti oxidative effect against auto immune disease induced the loss the follicle alopecia areata(7). 

Taking altogether, the combination of tomato and almond may process the activities in reduced risk of development and progression and treatment of Alopecia areata
People with higher risk of alopecia areata  due to family history, genetic mutation .... should drink 1 serving daily and people with alopecia areata should drink as much as they can, depending to digestive toleration.
Life Style and diet pattern changed are recommended

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(1) Oxidative stress and autoimmune skin disease by Shah AA1, Sinha AA.(PubMed)
(2) Oxidative stress in alopecia areata: a case-control study by Bakry OA1, Elshazly RM, Shoeib MA, Gooda A.(PubMed)
(3) Alopecia areata: updates from the mouse perspective by Sundberg JP1, Berndt A, Silva KA, Kennedy VE, Sundberg BA, Everts HB, Rice RH, King LE Jr.(PubMed)
(4) Retinoids putting the "a" in alopecia by Holler PD1, Cotsarelis G.(PubMed)
(5) Endogenous retinoids in the pathogenesis of alopecia areata by Duncan FJ1, Silva KA, Johnson CJ, King BL, Szatkiewicz JP, Kamdar SP, Ong DE, Napoli JL, Wang J, King LE Jr, Whiting DA, McElwee KJ, Sundberg JP,Everts HB.(PubMed)
(6) [Treatment of alopecia areata with vitamin A acid].[Article in German] by Much Th.(PubMed)
(7) The antioxidant role of paraoxonase 1 and vitamin E in three autoimmune diseases by Ramadan R1, Tawdy A, Abdel Hay R, Rashed L, Tawfik D.(PubMed)

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