Tuesday, March 8, 2016

The Practical Smoothie of Orange and Wolfberry Juice and Honey with ot Without Low Fat Milk for Reduced Risk and Treatment of Chronic Cough

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Chronic Cough with no B12 deficiency
Yield: 2 servings (about 8 ounces each)
1/4 cup wolf berry
1/8 cup honey
1 3/4 cups orange juice

The smoothie for reduced risk and treatment of Chronic Cough with B12 deficiency
Yield: 2 servings (about 8 ounces each)
1/4 cup wolf berry
1/8 cup honey
3/4 cups orange juice
1 cup low fat milk

1. Place tall ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Chronic Cough without induced side effects has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.
Orange(1) and Wolfberry(4) Juice and Honey(6) with or without Low Fat Milk in recent studies by renowned institution suggested that the combined ingredients may consist a potential effect for production of natural alternation in treating respiratory disease, including cough.

Cough is a continued reflection and natural reaction of lung to clear the large breathing passages from secretions, irritants, foreign particles, etc. 

Chronic cough is a condition of coughing lasting more than eight weeks in adult and 4 weeks in children, affecting night time sleep caused by some underlying health problems, including astroesophageal reflux disease (GERD).

In conventional medicine, gabapentin and morphine are prescribed most frequently as top medication to treat and induced positive effects on cough-related quality of life, but only gabapentin was recommended(9).

In traditional Chinese medicine, the formula Nin Jiom Pei Pa Koa has shown effectively in treatment of chronic cough and other condition such as sore throat, coughs, hoarseness, and loss of voice. You can buy them in any Chinese herbal store about $7.00 CAN. According to the China Academy of Traditional Chinese Medicine, King To Nin Jiom Pei Pa Koa had significant cough relieving and sputum removing effects through its anti inflammaoty activties(10).

According to University of Turin, patients with unexplained chronic cough are associated to vitamin B12 deficiency(3), as the vitamin supplement significantly improved symptoms and laryngeal, bronchial, and cough thresholds in oral administration.

Vitamin C, also known as L-ascorbic acid, a water-soluble vitamin, found abundantly in orange juice, is best known for its free radical scavengers activity and regenerating oxidized vitamin E for immune support in reduced risk of "morning cough", "chronic cough", "wheeze" and "wheeze ever(11).

According to the National Institute of Public Health and the Environment (RIVM), intake of vitamin C exhibited protective effects against respiratory symptoms in comparison to those with lower intake(2).

Dr.Goldman RD at the Canadian Paediatric Society, Drug Therapy and Hazardous Substances Committee, suggested, use of over counter medicine for treatment of cough in adult populations when cough frequency and severity, may cause medication errors and adverse events(3). Therefore, cough and cold therapies should consider intake of vitamin C and other forms of natural sources instead(3).

Wolfberry, also known as lycium fruits is the common name for the fruit of two very closely related species, the genus of Lycium, belongings to family Solanaceae, native to native to southeastern Europe and Asia. has been found effective in treatment of various human infectious diseases, including cough, according to the Hazara University Mansehra, Pakistan(4).


Dr. Cassileth B, professor at the Memorial Sloan-Kettering Cancer Center, said, " The berries of Lycium barbarum, a perennial plant native to Asia and southeastern Europe, have been used for centuries in traditional Chinese medicine to treat poor vision, anemia, inflammation, and cough"(6).
The fruit water extract also exhibited anti-inflammatory effect for treatment of cough through suppression of pro inflammatory cytokines(5).
Honey, the rich golden liquid is the miraculous product made by bees using nectar from flowers, is considered as one of healthy sweet food for replacing the use of white sugar and artificial sweetener by many people. Recently, it is considered as effective treatment of childhood cough, persistent post-infectious cough, according to the joint study lead by the Maastricht University Medical Center (MUMC)(7).

Dr. Ran D. Goldman, at the the College of Family Physicians of Canada said, "There is increasing evidence that a single dose of honey might reduce mucus secretion and reduce cough in children."(8).
In the study of honey for acute cough in children, Dr. Oduwole O and the research team at the University of Calabar Teaching Hospital (ITDR/P), insisted (without consideration of the adverse effect of conventional medicine of dextromethorphan) that honey may be better than 'no treatment' and diphenhydramine in the symptomatic relief of cough but not better than dextromethorphan(9).

Orange juice, containing the highest amount of vitamin C in comparison to other fruits may mimic the similar effects when use conjunction with wolf berry and honey for reduced risk and treatment of cough with no adverse effects.

People who are at increased risk of Chronic cough , due to family history, smoking,....should drink the juices at least one a day. People with Chronic cough should drink the juice as much as as they can depending to digestive toleration.
Life style and diet pattern change are recommended.

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References
(1) Dietary vitamin C intake is inversely related to cough and wheeze in young smokers.Omenaas E1, Fluge O, Buist AS, Vollmer WM, Gulsvik A.(PubMed)
(2) Dietary intake of antioxidant (pro)-vitamins, respiratory symptoms and pulmonary function: the MORGEN study by Grievink L1, Smit HA, Ocké MC, van 't Veer P, Kromhout D.(PubMed)
(3) Treating cough and cold: Guidance for caregivers of children and youth.[Article in English, French] by Goldman RD; Canadian Paediatric Society, Drug Therapy and Hazardous Substances Committee.(PubMed)
(4) Investigation of traditional medicinal floral knowledge of Sarban Hills, Abbottabad, KP, Pakistan. by Ijaz F1, Iqbal Z2, Rahman IU3, Alam J4, Khan SM5, Shah GM6, Khan K7, Afzal A8.(PubMed)
(5) Anti-inflammatory effect of Lycium Fruit water extract in lipopolysaccharide-stimulated RAW 264.7 macrophage cells by Oh YC1, Cho WK, Im GY, Jeong YH, Hwang YH, Liang C, Ma JY.(PubMed)
(6) Lycium (Lycium barbarum) by Cassileth B1.(PubMed)
(7) Honey and Beehive Products in Otorhinolaryngology: a narrative review by Henatsch D1, Wesseling F1, Kross KW1, Stokroos RJ1.(PubMed)
(8) Honey for treatment of cough in children by Ran D. Goldman, MD FRCPC(PMC)
(9) Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report by Gibson P1, Wang G2, McGarvey L3, Vertigan AE4, Altman KW5, Birring SS6; CHEST Expert Cough Panel.(PubMed)
(10) [Pharmacological studies of nin jion pei pa koa].[Article in Chinese] by Li ZL1, Dai BQ, Liang AH, Li GQ, Yang Q, Xue BY.(PubMed)
(11) Unexplained chronic cough and vitamin B-12 deficiency by Bucca CB1, Culla B, Guida G, Sciascia S, Bellone G, Moretto A, Heffler E, Bugiani M, Rolla G, Brussino L.(PubMed)

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