Thursday, August 11, 2016

Regular Walking Reduces Risk and Complications of hyperlipidemia in Older Adults

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Cholesterol is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat. However too much of it can be dangerous because cholesterol cannot dissolve in your blood. The special particle called lipoprotein moves this waxy, soft substance from place to place. If you have too much low density lipoprotein LDL that is known as bad cholesterol, overtime cholesterol can build up in your arterial walls causing blockage and leading to heart attack and stroke.
 High density lipoprotein in short HDL, is known as good cholesterol. It helps to carry bad cholesterol away from your arteries to the liver where it is eliminated.
High cholesterol in your blood can be dangerous, but it can be controllable through diet.

Regular physical activity has long been found to associate to the prevention of cancer, cardiovascular disease, and other chronic diseases, but regular walking contribution of reduced risk and complications of high blood cholesterol in the younger and older elderly have been lacking, probably due to the effectiveness of modern medication in syndrome of controlling(1).

The CDC analyzed data from 1999-2002 and 2005-2008 to examine the prevalence, treatment, and control of high LDL-C among U.S. adults aged ≥20 years, showed that.medication used to control of high LDL-C have had a prevalence rate of over 100%, from 14.6% to 33.2% between the periods(2).

Regular Walking of 30 to 60 minutes per session on 2 days per week for 12 weeks, according to the joint study led by the Dong-A University, not only lowered Plasma oxidised low-density lipoprotein concentrations but also improved the ratio of oxidised low-density lipoprotein to high-density lipoproteincholesterol significantly in comparison t. o baseline ratio(3) of that induced the reduced risk of cardiovascular-related health in older adults.

Dr. Neuparth MJ and colleagues at the Universidade do Porto in the study of moderate walking exercise on reduced chemerin levels in Portuguese patients with type 2 diabetes said, " The active patients, compared with the inactive, presented a trend toward higher levels of adiponectin and lower values of oxidized low-density lipoprotein." and " moderate walking in a regular basis was sufficient to reduce chemerin levels(involved actuvation of inflammatory and coagulation serine proteases.)"(4).

Cardiovascular disease, a complication of high blood cholesterol kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease, according to statistic and literature, hyperlipidemia is a well document risk factor for Cardiovascular Disease(7).

The joint study led by the University of Porto, of prospective cohort analysis among 4207 US men and women of a mean age of 73 years(standard deviation=6) who were free of CVD at baseline in the Cardiovascular Health Study suggested, walking reduces the incidence of CVD among older adults(6).

In fact, regular walking, according to Dr.Bassuk SS and Dr. Manson JE. not only retarded the complications of high blood cholesterol of retard the progression of asymptomatic coronary and peripheral arteriosclerosis, but also improved cardioprotective mechanisms of physical activity include reducing adiposity, blood pressure, diabetes incidence, dyslipidemia, and inflammation, and enhancing insulin sensitivity, glycemic control, fibrinolysis, and endothelial function(5).

(1) Prevalence of Cholesterol Treatment Eligibility and Medication Use Among Adults--United States, 2005-2012 by Mercado C, DeSimone AK, Odom E, Gillespie C, Ayala C, Loustalot F.(PubMed)
(2) Vital signs: prevalence, treatment, and control of high levels of low-density lipoproteincholesterol--United States, 1999-2002 and 2005-200 by Centers for Disease Control and Prevention (CDC)(PubMed)
(3) Low-volume walking program improves cardiovascular-related health in older adults by Park JH1, Miyashita M2, Takahashi M3, Kawanishi N4, Hayashida H5, Kim HS6, Suzuki K3, Nakamura Y3.(PubMed)
(4) The positive effect of moderate walking exercise on chemerin levels in Portuguese patients with type 2 diabetes mellitus by Neuparth MJ1, Proença JB, Santos-Silva A, Coimbra S.(PubMed)
(5) Physical activity and the prevention of cardiovascular disease by Bassuk SS1, Manson JE.(PubMed)
(6) Physical Activity and Risk of Coronary Heart Disease and Stroke in Older Adults: The Cardiovascular Health Study by Soares-Miranda L1, Siscovick DS2, Psaty BM2, Longstreth WT Jr2, Mozaffarian D2.(PubMed)
(7) Hyperlipidemia as a Risk Factor for Cardiovascular Disease by Robert H. Nelson, MDa,b,(PMC)

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