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Kuan Jin Teng is also known as Chinese tinospora stem. The sweet, slightly acrid and neutral herb has been used in TCM as anti-inflammatory agent and immune enhancer and to treat difficulty in urination, edema, constipation, rheumatism, influenza, hepatitis, stomachache, diarrhea, mastitis, acute cellulitis etc., as it expels Wind-Damp, soothes the sinews, promotes circulation, etc, by enhancing the functions of liver and spleen channels.
1. Tinosposides A and B (lignan glucosides)
2. Tinosinen (phenolic glycoside).
1. Anti-inflammatory activity
In the evaluation of Anti-inflammatory activities of ethanol extracts from nine vine plants used in traditional Chinese medicine used to treat inflammatory conditions against a panel of key enzymes relating to inflammation, including Tinospora sinensis (Lour.) Merrill, showed that All of the plant extracts showed inhibitory activities against at least one of the enzymes in various percentages depending upon the concentrations. The extract from S. suberectus was found to be active against all enzymes except COX-2. Its IC(50) values were 158, 54, 31 and 35 microg/ml in COX-1, PLA(2), 5-LO and 12-LO assays, respectively(1).
2. Inhibition of nitric oxide release
In the examination of the Inhibition of nitric oxide release by an aqueous extract of Tinospora tuberculata, showed that when the aqueous extract was added to lipopolysaccharide-stimulated murine macrophages, it inhibited NO release dose-dependently, and similar activity was found in a cell-free system using sodium nitroprusside as a NO donor(2).
1. Do not use the herb in newborn, children or if you are pregnant or breast feeding without first consult with your doctor or related field specialist
2. Do not use the herb in postpartum period
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