Tuesday, August 16, 2016

Traditional Chinese Medicine Herbal Therapy - Popular Chinese Herbs - Ji Xue Teng (Radix et Caulis Jixueteng)

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
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         Ji Xue Teng (Radix et Caulis Jixueteng)

Ji Xue Tang or Feng Xue Teng or Ma Lu Teng, Zi Geng Teng is also known as Radix et Caulis Jixueteng. The bitter, slightly warm and sweet herb has been used in TCM to treat irregular menses, enhance flow of menses, platelet count, treat rheumatoid arthritis, lower blood chilesterol, etc., as it moves and tonifies Blood, soothes the sinews, promotes circulation in the collaterals, etc., by enhancing the functions of heart, spleen and liver channels.

1. Jixuetengsterol
2. Tannin acid
3. Friedelin
4. Friedelinsterol
5. Taraxerone
6. β- Sitosterol
7. Campesterol
8. Calcium oxalate
9. Etc.

Health Benefits
1. Anti oxidative stress and inflammation
In the investigation of the effects of the water extracts of Millettia reticulata Benth (WEMRB) and its active compound (protocatechuic acid [PCA]) on acute hepatic injury and inflammation in CCl(4)-induced Sprague-Dawley rats, found that oral administration of WEMRB decreases the hepatotoxic effects by increasing glutathione-dependent antioxidant enzyme activity, thereby reducing oxidative stress and inflammation in CCl(4)-induced Sprague-Dawley rats, according to “Protective effect of Millettia reticulata Benth against CCl(4)-induced hepatic damage and inflammatory action in rats” by Hsu CC, Hsu CL, Tsai SE, Fu TY, Yen GC.(1).

2. Anticancer effects
In the study of to studyanticancer activity of flavonoid derivatives isolated from the stems of M. reticulata Benth. Six flavonoid derivatives including (-)-epicatechin (1), naringenin (2), 5,7,3′,5′-tetrahydroxyflavanone (3), formononetin (4), isoliquiritigenin (5), and genistein (6) in vitro,
indicated that genistein (6) had the strongest inhibitory activity with an IC(50) value of 16.23 microM in SK-Hep-1 human hepatocellular carcinoma cells. Treatment of SK-Hep-1 cells with genistein (6) caused loss of mitochondrial membrane potential. Western blot data revealed that genistein (6) stimulated an increase in the protein expression of Fas, FasL, and p53. Additionally, treatment with genistein (6) changed the ratio of expression levels of pro- and anti-apoptotic Bcl-2 family members and subsequently induced the activation of caspase-9 and caspase-3, which was followed by cleavage of poly(ADP-ribose) polymerase (PARP). These results demonstrate that genistein (6) induces apoptosis in SK-Hep-1 cells via both Fas- and mitochondria-mediated pathways, according to “Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells” by Fang SC, Hsu CL, Lin HT, Yen GC.(2).

3. Antiviral effects
In the examination of theantiviral effects of the aqueous extract of Spatholobus suberectus Dunn. (A.E.), a Chinese medicinal herb, against coxsackievirus B3 (CVB3), showed that .E. exhibited obvious antiviral: effects in vivo, and serum samples obtained from the rats with oral administration of A.E. (10 μg/mL, 5 μg/mL), reduced the virus titers in the infected myocardial cells (3.00±0.70, 3.55±0.52, P<0.01), according to “Antiviral effects of aqueous extract from Spatholobus suberectus Dunn. against coxsackievirus B3 in mice” by Pang J, Guo JP, Jin M, Chen ZQ, Wang XW, Li JW.(3)
4. Etc.

Side Effects
1. Do not in case of yin deficiency with fire
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist
3. Etc.

(1) http://www.ncbi.nlm.nih.gov/pubmed/19735183
(2) http://www.ncbi.nlm.nih.gov/pubmed/19994890
(3) http://www.ncbi.nlm.nih.gov/pubmed/21717161

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