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Jie Shi or Zhi Shi is also known as mature fruit of bitter orange. The bitter, sour, acrid and slightly cold herb has been used in TCM as diuretics and to raise blood pressure, improve the strength of contraction and tension of the uterus, stimulate the smooth muscle of the digestive tract, treat constipation, cough with abundance of phlegm, etc., as it moves Stomach-Qi and Spleen-Qi, etc., by enhancing the functions of stomach, and large intestine channels.
3. Nobiletin, 5-0 -desmethyl nobiletin
1. Anti fungal activity
In the investigation of fumigant toxicities of the peel essential oils of Citrus sinensis var. pêra (LP), C. sinensis var. mimo (LM), and C. aurantium (LL) cultivated in northeast Brazil were evaluated against Tetranychus urticae, showed that the most potent fumigant toxicity was found with LL oil, with an LC50 value of 1.63 microL/L air, followed by the oils from LM and LP with LC50 values of 2.22 microL/L air and 4.63 microL/L air, respectively, according to “Acaricidal activity against Tetranychus urticae and chemical composition of peel essential oils of three Citrus species cultivated in NE Brazil” by Araújo CP Jr, da Camara CA, Neves IA, Ribeiro Nde C, Gomes CA, de Moraes MM, Botelho Pde S.(1).
1. Do not use the herb in case of Qi deficiency or spleen and stomach deficiency
2. Do not use the Huang Bai in newborn, children or if you are pregnant or breast feeding with out approval first with the related field specialist
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