Herbal Aloe Vera Improves the Function of Immune System with No Side Effects

Scientists may have found a natural ingredient for the enhancement of the immune system with no side effects, according to studies.

The immune system is the set of cells associated with the activity against antigens or infectious agents.
It is one of the body's defense system against diseases.

The immune system does a great job of keeping people healthy and preventing infections.

Immune dysfunction is a chronic condition, depending on the parts of the immune system affected.

There are 2 types of immune dysfunction. The underactive immune system is also known as weakened immune system People with the underactive immune system are susceptible to infection, recurrent infections, autoimmune disorders, damage to heart, lungs, nervous system or digestive tract, increased risk of cancer, malnutrition, and death from serious infection.

On the other hand, the active immune system is also known as autoimmune diseases. In this case, patients suffer diseases associated with the immune system attacks the body tissue.

Immunomodulation is a process in which an immune response is altered to the desired level. In other words, under the immunomodulatory effect, the immune system is responding correctly to the desire of the body, regardless of types of immune dysfunction.


Dr. Jeffrey A. Bluestone, the lead scientist in the study "Current and Future Immunomodulation Strategies to Restore Tolerance in Autoimmune Diseases" wrote, "Considerable progress has been made in the immunomodulation of autoimmune diseases and the understanding of the complex molecular and cellular pathways targeted by novel treatments".


And "... a number of immunotherapies have become the standard of care and greatly improved the clinical outcome and quality of life of patients with some autoimmune diseases".


These results strongly suggested that immunomodulation can be used for the prevention and treatment of under and overactive immune function.


Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.

The herbal plant has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results.

The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.

They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.


With an aim to find the pharmacological potential of Aloe arborescens Miller leaf components against the immune dysfunction, researchers examined the to immune modulatory effects on the Sparus aurata fibroblast cell line SAF-1.

According to the application of Aloe extract at different concentrations (1.2-4.8 mg ml(-1)) for various times (24-72 h) for the treatment of the cells, the lowest concentration did not provoke any cellular damage observable by SEM and did not affect ATP amounts after 24 and 48 h, while even induced a significant increase over controls after 72 h.

However, the Aloe extract at a concentration of 1.2 mg ml(-1)) exerted a powerful immune stimulation in exhibiting an effect on interconnected genes in the SAF-1 cells involved in different aspects of the immune responses.

Researchers at the end of the experiment wrote, "A. arborescens to prevent or oppose bacterial and viral fish diseases and to face, as an alternative strategy based on natural plant extracts, the growing unwillingness to rely upon standard solutions involving antibiotics or antimicrobial chemicals".


Further, the investigation of the effect of an aloe polymannose multi-nutrient complex (APMC) formula on cognitive and immune functioning over 12 months among adults diagnosed with AD.

The participants were given to 4 teaspoons of the formula per day. The results were assessed at baseline and 12 months.


The formula demonstrated a significantly improved at 9 and 12 months compared to baseline, and 46% of our sample showed clinically-significant improvement (≥4-point change) from baseline to 12 months, according to the mean ADAS-cog cognition score.


Participants showed a significant decrease in protein associated with immune response in the activation of proinflammatory cytokines with few, temporary adverse reactions.


In other words, the formula displayed strong immune modulatory effects in regulating the immune responses on patients with AD.

Taken altogether, herbal Aloe vera may be considered a functional remedy in regulation and adjustment of the immune system against stimuli, including allergens, infectious pathogens with no side effect.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.


References
(3) The inner gel component of Aloe vera suppresses bacterial-induced pro-inflammatory cytokines from human immune cells. by Habeeb F, Stables G, Bradbury F, Nong S, Cameron P, Plevin R, Ferro VA.(PubMed)
(4) Immune modulatory effects of Aloe arborescens extract on the piscine SAF-1 cell line. by Picchietti S, Bernini C, Belardinelli MC, Ovidi E, Taddei AR, Guerra L, Abelli L, Fausto AM.(PubMed)
(5) The effect of an aloe polymannose multinutrient complex on cognitive and immune functioning in Alzheimer's disease. by Lewis JE, McDaniel HR, Agronin ME, Loewenstein DA, Riveros J, Mestre R, Martinez M, Colina N, Abreu D, Konefal J, Woolger JM, Ali KH.(PubMed)
(4) Current and Future Immunomodulation Strategies to Restore Tolerance in Autoimmune Diseases by Jeffrey A. Bluestone and Hélène Bour-Jordan. (PMC)