Monday, April 8, 2019

Herbal Chamomile, the Best Neuro-protective Remedy

Herbal Chamomile processed a high amount of antioxidant may have a strong and profound neuroprotective effect against the onset of cognitive impairment, according to studies.

Cognitive impairment is a medical condition associated with a decline in cognitive abilities, including memory and thinking skills.

Approximately 15 to 20% of cognitive impairment are diagnosed in people age 65 or older. However, if the condition of cognitive impairment gets worse over time, it eventually leads to dementia that compromises social and/or occupational functioning.


In the early stage of cognitive impairment, patients may experience symptoms of hallucinations. delusions, personality changes, apathy, and some depression and anxiety symptoms.


If you are experiencing some of the above symptoms, please make you check with your doctors to rule out the possibility.


Although there are many factors associated with the onset of cognitive impairment, some researchers suggested that aging is the major cause of the condition in the Western world.


Therefore, finding a strategy for the delay of cognitive impairment in the elderly has become more urgent. Dr. Blanka Klimova, and colleagues in the dementia team at the University Hospital Hradec Kralove and University Hradec Kralove in the concern of the risk of cognitive impairment in aging wrote, " physical activities, such as walking and aerobic exercises, music therapy, adherence to Mediterranean diet, or solving crosswords, seem to be very promising lifestyle intervention tools"

And, "The results indicate that non-pharmacological lifestyle intervention activities should be intense and possibly done simultaneously in order to be effective in the prevention of cognitive decline. In addition, more longitudinal randomized controlled trials are needed in order to discover the most effective types and the duration of these intervention activities in the prevention of cognitive decline, typical of aging population groups"


Chamomile is also known as camomile, the common name of many species daisy-like plants in the family Asteraceae.

The herb has been used in traditional medicine as an antispasmodic and anti-inflammatory constituent and for the treatment of menstrual cramps and sleep disorders, reduce cramping and spastic pain in the bowels, relieve excessive gas and bloating in the intestine, etc.

Scientists on finding an herbal remedy which processes neuroprotective effects examined the chamomile activity against the onset of oxidative stress which is considered a key role in the pathophysiology of many neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, Huntington's disease.

Aluminum fluoride (AlF₄⁻)-induced oxidative stress in rats selected to the study were divided randomly into group I received normal saline; group II received AlF₄⁻ (negative control); groups III, IV, and V received 100, 200, and 300 mg/kg, orally, German chamomile methanol extract (GCME) along with AlF₄⁻; and group VI received quercetin (25 mg/kg, i.p.) + AlF₄⁻, respectively.

The experiment included a 10 days treatment with GCME before the animal induced oxidative stress by administering AlF₄⁻ through drinking water for 7 days.


Administration of GCME inhibited the levels of oxidative stress through increasing the production of antioxidant enzymes produced by the host and decrease in lipid peroxidation (LPO).
Compared with the negative control group (P < 0.001), chamomile displayed a potent neuroprotective action against oxidative brain damage.

In rat induced oxidative stress by global cerebral ischemia/reperfusion (I/R) injury, application of methanolic extract showed dose-dependent neuroprotective activity by a significant decrease in lipid peroxidation (LPO) and increase in the superoxide dismutase (SOD), catalase (CAT), glutathione (GSH) similar to that of the above study.
The treatment group also showed a significantly reduced vertebral infarction area in extract treated groups, compared to the untreated group.


Dr. Chandrashekhar VM, the lead scientists, said, "The methanolic extract of Matricaria recutita L. showed potent neuroprotective activity against global cerebral ischemia/reperfusion injury-induced oxidative stress in rats".

Taken altogether, herbal chamomile which demonstrates the brain neurons protective effect against oxidative stress in the initiation of neurodegenerative diseases, may be considered a functional remedy for the prevention and combined with primary therapy for the treatment of dementia.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.





Sources
(1) Neuroprotective activity of Matricaria recutita against fluoride-induced stress in rats by Ranpariya VL1, Parmar SK, Sheth NR, Chandrashekhar VM.(PubMed)
(2) Neuroprotective activity of Matricaria recutita Linn against global model of ischemia in rats vy Chandrashekhar VM1, Ranpariya VL, Ganapaty S, Parashar A, Muchandi AA(PubMed)
(3) Cognitive decline in normal aging and its prevention: a review on non-pharmacological lifestyle strategies by Blanka Klimova,1,2 Martin Valis,2 and Kamil Kuca. (PMC)

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