Green Tea in Ameliorated Risk and Treatment of Lifestyle-Related Diseases

Green tea is found to consist of a therapeutic and sustainable effect in reduced risk and progression of lifestyle diseases, some scientists postulated

Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.

Lifestyle diseases are a class of diseases associated with the way a person or group of people lives, including atherosclerosis, heart disease, and stroke; obesity and type 2 diabetes....and diseases precipitated by smoking and alcohol and drug abuse.

Epidemiological studies suggested that lifestyle-related diseases may be preventable with the change of lifestyle accompanied by the intake of some nontoxic agents.


Differentiation of the effect of green tea in attenuated risk and treatment of lifestyle-related diseases was found to associate to some mechanisms involving number of aspects, particularly, in gene facilitation.


In animal model, green tea administration inhibited risk and symptoms and progression of chronic inflammatory diseases such as rheumatoid arthritis and multiple sclerosis, through regulation of tumor necrosis factor (TNF-alpha) gene in expression of inflammatory cytokines in promoted systematic inflammation in the acute phase of infection caused by damage and injure tissues, in modulated the activation of NF-kappaB signaling pathway related to cellular response in induction of anti and pro-inflammatory stimulation and transcription factor complex (AP-1) in initiation of inflammation against foreign invasion.


The inhibition of inflammatory cytokines expression reduced symptoms of pain, reddish skin, swelling without limiting the protective effect of the immune system to prevent damage tissues against the invasion of foreign substances.

Further analysis of chronic inflammatory diseases, in transgenic mice model with human idiopathic pulmonary fibrosis, suggested that injection of green tea in 4 months demonstrated a significant activity in ameliorated overexpression of TNF-alpha in stimulated production of pro-inflammatory cytokines and interleukin (IL)-6 in initiated inflammatory expression in cellular defense in response to infections and tissue injuries in the lung.

In lifestyle-related diseases of cardiovascular disease, intake of green tea beverage or extract expressed a significant reduction in serum total cholesterol and LDL-cholesterol concentrations, without affecting the levels of HDL-cholesterol.

Additionally, in patients with type 2 diabetes mellitus, green tea extract catechin injection improved fasting glucose levels without affecting the hemoglobin A1c (HbA1c) level, which is an predictor of type 2 diabetes onset and green tea consumed 5 or more cups per day was associated to a strongly and positively inverse association to risk of type 2 diabetes mellitus.
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More amazingly, after taking into account of other confounders, Dr. Sueoka E, the lead scientist suggested that intake of green tea, containing catechins and caffeine, 5 or more cups per day exhibited a potential and therapeutic effect for bodyweight management, without going into details.


According to the prospective cohort study in Saitama Prefecture, Japan, green tea injection of over 10 cups per day, displayed a substantial effect in decreased relative risk of death from all causes in patients with cardiovascular disease, particularly, in stroke mortality.

Take together, there is no doubt that green tea with abundantly bioactive phytochemicals may be considered as a functional food to reduced risk, progression, and treatment of lifestyle-related disease, but a change of lifestyle is always recommended.




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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Human clinical studies of tea polyphenols in allergy or life style-related diseases by Maeda-Yamamoto M1.(PubMed)
(2) A new function of green tea: prevention of lifestyle-related diseases by Sueoka N1, Suganuma M, Sueoka E, Okabe S, Matsuyama S, Imai K, Nakachi K, Fujiki H.(PubMed)