Aloe Vera, the Natural Whole Food Medicine to Restore Normal Levels of Cholesterol

Dietary Aloe vera improved plasma lipid profile, through enhancing antioxidant and hepatoprotective capacities, a study by a renowned institute suggested.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.

Cholesterol is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts for digested fat. However too much can be dangerous because cholesterol cannot dissolve in your blood.

According to the joint study lead by the Nanjing Agricultural University, oral administration of less than or equal to 1.88, 1.86, and 2.79 %/kg in test animals showed to improve plasma lipid profile status, antioxidant, and hepatoprotective enzyme activities.

Dr. Gabriel NN, the lead author suggested, animal fed with Aloe Vera exhibited a significantly elevated high-density lipoprotein in 0.5 and 1 % Aloe/kg with no significant changes in low-density lipoprotein. After 8 weeks of treatment, the group fed dietary Aloe at 4 %/kg expressed a significantly reduced total cholesterol and triacylglycerol.

Also in animal study of 5 treatment groups of rats (n = 7) fed with experimental diets: a normal control diet, a hypercholesterolemic diet (HD), hypercholesterolemic diet (HD) + Lactobacillus rhamnosus GG (LGG), hypercholesterolemic diet (HD) + AV gel, and hypercholesterolemic diet (HD) + Lactobacillus rhamnosus GG (LGG) + AV gel, group fed with combination of LGG and AV gel exerted a therapeutic potential to decrease cholesterol levels and the risk of cardiovascular diseases

Furthermore, the efficacy of aloe vera in inhibited of high blood cholesterol is the result of the complex functions in restore normal levels of high-density lipoprotein-cholesterol, low-density lipoprotein-and very low-density lipoprotein-cholesterol, through blocking altered fatty acid composition in the liver and kidney.

The most effective dose of oral administration of Aloe vera gel extract is at a dose of 300 mg/kg body weight per day to STZ-induced diabetic rats.


Dietary Aloe Vera has shown to inhibit lipid peroxidation and restore normal ratio levels of blood cholesterol in some animal studies, human trials are necessary to validate this claim.



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Source
(1) Dietary Aloe vera improves plasma lipid profile, antioxidant, and hepatoprotective enzyme activities in GIFT-tilapia (Oreochromis niloticus) after Streptococcus iniae challenge by Gabriel NN1,2, Qiang J3,4, Ma XY3, He J3,4, Xu P5,6, Liu K3,4.(PubMed)
(2) Probiotic Lactobacillus rhamnosus GG and Aloe vera gel improve lipid profiles in hypercholesterolemic rats by Kumar M1, Rakesh S, Nagpal R, Hemalatha R, Ramakrishna A, Sudarshan V, Ramagoni R, Shujauddin M, Verma V, Kumar A, Tiwari A, Singh B, Kumar R.(PubMed)
(3) Beneficial effects of aloe vera leaf gel extract on lipid profile status in rats with streptozotocin diabetes by Rajasekaran S1, Ravi K, Sivagnanam K, Subramanian S.(PubMed)