Aloe vera may be the next potential topical medicine used for the treatment of oral HSV-1 infections without exerting any toxicity, the study by the renowned institute suggested.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits, used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.
Herpes simplex is a contagious disease caused by human herpesvirus 1 and 2, the 2 members of the herpes virus family.
According to the joint study lead by the Shiraz University of Medical Sciences, gel extraction with concentrations of Aloe vera (0.2, 0.5, 1, 2, and 5%) exhibited anti-HSV-1 activity assessed by plaque reduction assay.
Dr. Rezazadeh F, the lead author of the study said, "The inhibitory effect of various concentrations of Aloe vera was observed one hour after the Vero cell was infected with HSV-1. However, there was no significant difference between the two serial concentrations".
Acemannan, an extracted polysaccharide from Aloe vera, has shown to exhibited antiviral activities against herpes simplex virus type 1 (HSV-1), in vivo through activation of immune responses.
A combination with azidothymidine(an antiretroviral medication) and acyclovir(an antiviral medication) administration acted synergistically to inhibit the replication of HIV-1 and herpes simplex virus type 1 (HSV-1), respectively.
In fact, the effects of the combination against U1 cells infected with HIV-1, are also attributed to the function of blocking the potentiate of virus replication without inducing toxicity.
Although Aloe Vera has shown to inhibit the replication of HSV-1 activity through its antiviral property, a more precise understanding of the biological activities is necessary before developing Aloe vera as a pharmaceutical source.
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Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Sources
(1) Assessment of Anti HSV-1 Activity of Aloe Vera Gel Extract: an In Vitro Study by Rezazadeh F1, Moshaverinia M1, Motamedifar M2, Alyaseri M3.(PubMed)
(2) Acemannan, an extracted polysaccharide from Aloe vera: A literature review by Sierra-García GD, Castro-Ríos R, González-Horta A, Lara-Arias J, Chávez-Montes A.(PubMed)
(3) In vitro evaluation of the synergistic antiviral effects of acemannan in combination with azidothymidine and acyclovir by Kahlon JB1, Kemp MC, Yawei N, Carpenter RH, Shannon WM, McAnalley BH.(PubMed)
Please note that all articles written by Kyle. J. Norton are for information and education only, please consult with your doctor or related field specialist before applying. http://diseases-researches.blogspot.ca/
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