Aloe Vera, the Natural Whole Food Medicine for Reduced Symptoms and Treatment of Oral Submucous Fibrosis

A study from renowned institutes suggested that injection of aloe vera may be reduced risk and treatment of oral submucous fibrosis.

Oral submucous fibrosis (OSMF or OSF) is a chronic condition involved in the oral cavity caused by an inflammatory reaction and progressive fibrosis of the submucosal tissues.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It is very popular for commercial cultivation due to its health benefits, used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.

According to the Sibar Institute of Dental Sciences, after 3 months of Aloe Vera treatment, patients with oral submucous fibrosis (OSMF or OSF) showed reduced levels of burning sensation and improved mouth opening.

In a total of 20 patients with oral submucous fibrosis, 10 in each group; group A subjects received 5 mg of aloe vera applied topically three times daily for 3 months and group B subjects received antioxidant capsules twice daily for 3 months study, group treated with aloe vera showed a statistically significant improvement of symptoms in comparison to control group.


Dr. Sudarshan R, the lead researcher in the study said, ". Aloe vera showed a statistically significant reduction in burning sensation (P = 0.008), improvement in mouth opening (P = 0.02), and cheek flexibility (P = 0.01) on comparing with the antioxidant group"


In support of the above differentiation, a double-blind, placebo-controlled, parallel-group randomized controlled trial conducted on 60 subjects with OSMF by Institute of Dental Sciences, Bareilly, Uttar Pradesh, insisted that group receiving aloe vera had a significant improvement in most symptoms of OSMF (P < .01) compared with the non-aloe vera group,

Other researchers suggested that the analgesic effects aloe vera in reduced symptoms and treatment of oral submucous fibrosis should be accompanied with proper habit restriction together with physiotherapy exercises.


The study also emphasized the effectiveness of treatment in ameliorated symptoms, such as burning sensation, mouth opening, tongue protrusion and cheek flexibility in comparison to other treatment groups.

Taking together, no doubt, aloe vera is effective in attenuated symptoms and treatment of patients with oral submucous fibrosis, but intake of the large amounts should only be prescribed by the herbalist.



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Sources
(1) Aloe vera in the treatment for oral submucous fibrosis - a preliminary study by Sudarshan R1, Annigeri RG, Sree Vijayabala G.(PubMed)
(2) Efficacy of aloe vera gel as an adjuvant treatment of oral submucous fibrosis by Alam S1, Ali I, Giri KY, Gokkulakrishnan S, Natu SS, Faisal M, Agarwal A, Sharma H.(PubMed)
(3) Effectiveness of Aloe Vera and Antioxidant along with Physiotherapy in the Management of Oral Submucous Fibrosis by Singh N1, Hebbale M2, Mhapuskar A2, Ul Nisa S2, Thopte S2, Singh S2.(PubMed)