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Cirrhosis is defined as a condition of irreversible scarring liver as a result of liver tissue by fibrosis due to final phase of chronic liver diseases of that can lead to poor function of the liver and liver failure. According to the statistics, Number of discharges with chronic liver disease or cirrhosis as the first-listed diagnosis: 101,000 in 2009 and Deaths per 100,000 population: 10.3 in 2010(a). Hepatitis B infection cause of the disease is very prevalent in South-East Asia.
A. Treatments of cirrhosis depend not on the underline causes and stage of the diseases
Hepatitis causes of cirrhosis
Hepatitis is characterized by the destruction of a number of liver cells and the presence of inflammatory cells in the liver tissue caused by excessive alcohol drinking, disorders of the gall bladder or pancreas, including medication side effects, and infections. There are many other infective agents that can cause inflammation of the liver, or hepatitis. However, the term is unfortunately commonly used to refer to a particular group of viruses such as Hepatitis A, B, and C.
A.3.1. In conventional medicine perspective(82)
1. Liver Detoxification
Strengthens the immune system with vitamins, nutritional supplements and herbs that we have been discussed lengthily in other articles.
2. Ozone therapy
Ozone oxidizes the cells of the body systemically. It stimulates enzymes and phagocytes of the white blood cells which chew up the viruses and the bacteria in the blood. It also activates alpha interferon, gamma interferon, interleukin II and tumor necrosis factor. It is effective in treating hepatitis B patients with high successful rate.
3. Lamivudine therapy
Combining vaccine therapy with lamivudine has improved therapeutic potential for chronic hepatitis B. It helps to strengthen the immune system fighting against the hepatitis B virus specially with patients with chronic HBV infection and active viral replication.
4. Interferon-alpha therapy
Chronic hepatitis B virus (HBV) infection is a serious health problem because of its worldwide distribution. There are over 350 million people in the world infected with chronic HBV, 75% of whom live in the Asia-Pacific region. Interferon-alfa and direct antiviral agents such as lamivudine and adefovir are effective in the therapy of chronic HBV infection but only with some success, particularly in perinatally infected patients, patients with lower ALT levels and those with negative chronic hepatitis B.
5. Pegylated interferon
Pegylated interferon may be considered the best choice of treatment for patients with chronic hepatitis B infection. This therapy has been shown to be superior to both conventional interferon as well as lamivudine in the treatment of both hepatitis B positive and negative chronic hepatitis B with successful rates of 35-45%.
A.3.2. In herbs medicine perspective(83)
1. Red clover
Rich in micro-nutrients it possesses activity against several bacteria. A good dietary supplement of vitamin A and Iron, it also contains B- complex, vitamins C,F, and P, some selenium, cobalt, nickel, manganese, sodium and is particularly rich in magnesium, calcium and copper.
2. Oregon grape root
The herb stimulates the action on the liver and is one of the best blood cleansers. Mild stimulant to the thyroid functions and aids in the assimilation of nutrients.
Echinacea is an immuno stimulant. Enhancing the body's resistance against both bacterial and viral infections it is probably the best detoxifying agent in Western Herbalism. It cleanses the blood and lymph systems, helps arrest pus formation and tissue putrefaction.
Sarsaparilla purifies the urino-genital tract, dispelling all infection and inflammation. It's purifying action extends to the nervous system and is therefore useful in many nervous disorders. Sarsaparilla's diaphoretic and blood cleansing action is useful for rheumatic inflammation.
5. Licorice root
Licorice root is a natural anti-inflammatory agent. It helps to increase the secretion of digestive enzymes and bile and is widely regarded as the supreme liver tonic.
It clears congestion, reduces swelling and dispels toxins via the skin, kidneys and bowel. It is a nutritive and rejuvenatory tonic . Historically it has been used to support the action of the kidneys in urinary tract infections.
Dandelion cleanses the liver, kidneys, lymph and bowel and is ideal for toxic blood conditions. It increases the secretion of digestive enzymes and bile and is widely regarded as the supreme liver tonic.
A.3.3 In Traditional Chinese medicine perspective(84)
1. Natural schisandra,
Schisandradra contains essential oils, acids and lignans that help to regenerate liver tissue caused by excessive drinking of alcohol and hepatitis virus.
2. Milk thistle,
consists of three components silybin, silydianin, and silychristin that help to reverse liver damage from alcohol, liver injure in result of chronic hepatitis and sloe the advance of cirrhosis.
3. Dan shen Danshen
is frequently used for these problems in combination with other herbs in treating liver diseases such as cirrhosis, fibrosis, and chronic hepatitis B.
Lycii contains high amount of beta-carotene that helps to nourish and tonify liver and kidney.
5. Chinese licorice
Licorice contains a compound called glycyrrhizin and has a long history of medicinal use in both Eastern and Western systems of medicine in treating infections caused by viruses, such as hepatitis.
Astragalus is used conbination with other Chinese herbs are thought to possess properties in treating cancer, viral infection and immune system disorder. Astragalus is an ingredient in
7. Baikal scullcap
Baikal scullcap contains a chemical of baikalin that helps liver to detoxification and fight against liver infection.
This herb has been used over thousand years in Chinese history in treating a variety of diseases such as high blood fat, heart disease, strengthen immune system as well as hepatitis.
9. American ginseng
American ginseng contain the ginsenosides ingredient that is effective in preventing GalN-induced liver cell damage and is a useful agent for chemoprevention of cancer or inflammatory diseases such as liver infection by hepatitis virus.
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