Tuesday, June 28, 2016

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: Foods for Kidney Yang deficiency - Garlic In TCM

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).


Management and Treatment according to Traditional Chinese Medicine Perspective

While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.

Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).

Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into                    

                           Kidney yang deficiency

Along with common symptoms mentioned above, women with PCOs diagnosed with kidney yang deficiency may also experience yang vacuity induced cold expressive syndrome, including
lumbago, cold limbs, fatigue, cold aversion, feverish sensation in chest, palms and soles(1573),
difficulty in urination, enuresis, incontinence, declining libido and edema(1574) as a result of kidneys no longer perform their function in store fluid to moister and warm the body for healthy function in the body's organs and tissues, inducing adrenal insufficient chronic lower back pain(1575)(1580), depression(1575), hypothyroidism(1579)(1575), nephritis(1578)(1575), ...(1575), leading to failure in transform damp heat expression, promoted accentuation of inflammatory development of phlegm(1583).
Kidney yang deficiency has shown to alter carbohydrate and lipid metabolisms (free fatty acids, 1-monolinoleoylglycerol, and cholesterol), gut microbiota metabolism (indole-3-propionic acid), indued anovulatory infertility( 1581) and hypertension(1582) of which related to symptoms of PCOs(1576)(1577).

                                        Foods for kidney yang deficiency

Kidney yang deficiency can be managed and treated in part with a diet of fresh and cooked warming foods.
1. Garlic
Garlic (Allium sativum) is a species in the onion genus, belonging to family Amaryllidaceae, native to central Asia. It has been used popularly in traditional and Chinese medicine in treating common cold(1587)(1588) and flu(1589)(1590), blood pressure(1591)(1592), cholesterol levels(1593)(1594), natural antibiotic(1595)(1596), cancers(1597)(1598)(1599) etc....(1585).
According to traditional Chinese medicine, the acrid, warm herbal da suan expresses its tonification of yang through enhancing function of large intestine, lung, spleen, stomach channels(1586).

Chemical constituents(1586)
1. Allyl methyl sulfide
2. Diallyl sulfide
3. 6-methyl-1-thio-2
4. 4-cyclohexadiene
5. Dimethyl sulfide
6. Divinyl sulfide
7. Dimethyl disulfide
8. Allyl methyl disulfide
9. Dithiocyclopentene
10. 5-methyl-1
11. 2-dithio-3-cyclopentene
12. Allyl propyl disulfide
13. 2-dithio-3-cyclopentene
14. 4-methyl-1
15. 3-vinyl-1
16. 2-dithio-4-cyclohexene
17. 3-vinyl-1
18. 2-dithio-5 cyclohexene
19. Cysteine,
20. Histidine
21. Lysine
22. Etc.

Epidemiological literature suggested that garlic also displays anti metabolic syndrome(1602)(1603), including obesity(16000)(1601), elevated blood pressure(1591)(1592), elevated fasting plasma glucose(1604)(1605), high serum triglycerides(1604)(1602), and low high-density lipoprotein (HDL)(1593)(1594)(1604) levels, insulin resistance(1606)(1607), proinflammation(1609)(1608) and renal damage(1610)(1611), reduced risk of cardiovascular disease(1612)(1613) and diabetes, probably through its effects on carbohydrate and lipid(1601) modulation via anti inflammatory(1606) and antioxidant(1603)(1606) mechanisms. All these factors may be the reasons of which garlic was recommended by modern traditional Chinese medicine doctors for management and treatment of PCOs' women who were diagnosed with kidney yang deficiency.

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References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
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(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
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(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) bny by Liqin Zhao
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(1575) Kidney Yang Deficiency: Use Warming Foods and Moxibustion By Jody Smith(Empow her)
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[Article in Chinese] by Wu F, Zhang PQ, Wang XQ, Nie LF, Fu XJ, Peng W, Wang Y, Li J, Bi YP, Mi XH, Ding XQ, He LQ.(PubMed)
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(1585) Popular #Herbs - #Garlic (Allium sativum) by Kyle J. Norton
(1586) Da Suan, Garlic(Complementary and Alternative Healing University)
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(1590)A strategic call to utilize Echinacea-garlic in flu-cold seasons by Abdullah T.(PubMed)
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(1595) A comparison of the antimicrobial activity of garlic, ginger, carrot, and turmeric pastes against Escherichia coli O157:H7 in laboratory buffer and ground beef by Gupta S1, Ravishankar S.(PubMed)
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