Monday, June 27, 2016

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome:The B Vitamins

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).


Management and Treatment according to Traditional Chinese Medicine Perspective

While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches.

Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).


The Dietary Suggestion, Life Style Modification and Nutritional Supplements according to TCM
According to Angela Warburton(1249), a doctor of Traditional Chinese Medicine practicing in Toronto, Canada, incorporating the proper dietary and lifestyle modifications, may make a BIG difference in the long-term for treatment of PCOs(1249).


                       The Nutritional Supplements 






B. Micro nutrient supplements

1. B Vitamins
[Vitamin B1 (thiamine), Vitamin B2 (riboflavin), Vitamin B3 (niacin or nicotinic acid), Vitamin B5 (pantothenic acid), Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine), Vitamin B7 (biotin), Vitamin B9 (folic acid) and Vitamin B12 (various cobalamins; commonly cyanocobalamin or methylcobalamin in vitamin supplements)](1416)

B vitamins, a class of water-soluble vitamins, coexisted in the same foods, play an important role in cell metabolism, found in many foods, including legumes (pulses or beans), whole grains, potatoes, bananas, chili peppers, tempeh, nutritional yeast, brewer's yeast, and molasses(1416). According to studies, deficiency of certain members of B vitamins may disrupt cell metabolism, leading to risk of cancers(1417)(1418)(1419)(1420) and metabolic syndrome(1428).
a. Vitamin B1 (thiamine)
Deficiency of vitamin B1 may contribute to dyslipidemia(1421)(1427) and induce vascular complications in clinical diabetes(1421)(1422)(1423), metabolic defect(1424), cardiovascular diseases(1245), hypertension(1426), insulin resistance(1427), etc....

b. Vitamin B2 (riboflavin)
Deficiency of vitamin B2 has shown to decrease immune efficiency(1429)(1430) and anti oxidant status(1429), induce abnormal blood glucose level(1431), migraine(1432)(1433), various skin diseases(1434), hypertension(1435), hyperlipidemia(1436), etc...

c. Vitamin B3 (niacin or nicotinic acid)
Deficiency of vitamin B3 may contribute to low-grade chronic inflammation (metaflammation)(1437), reduce the effects on metabolic regulation(1437), including type 2 diabetes(1437), obesity(1437), and cardiovascular disease(1437), pigmentary disorders(1438) and acne(1438), etc....

d. Vitamin B5 (pantothenic acid)
Deficiency of vitamin B5 has shown to induce acne vulgaris(1439), hypertension(1440)(1441), a decrease in total antioxidant status(1442), insulin sensitive(1443), reduced diabetic cardiovascular function and cardiac performance(1444), etc...

e. Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine)
Deficiency of vitamin B6 may display sensorimotor peripheral neuropathy(a decreased ability to move or feel (sensation) due to nerve damage)(1445), hyperhomocysteinemia, a possible risk factor of morbidity and mortality associated with cardiovascular disease(1446), abnormal glucose levels(1431), endothelial dysfunction(1447), diabetes(1447) and inflammation(1447), reduce sympathetic activity and insulin-response, etc...

f. Vitamin B7 (biotin)
Deficiency of vitamin B7 has shown to contribute to genetic instability causes of DNA damage(1448) inducing cancers(1449) and a risk a factor in some neurodegenerative diseases(1449)m diffuse hair loss(1450), periorificial or acral dermatitis(1451), insulin sensitivity(1452) and glucose uptake(1452), risk of diabetes(1452), etc...

g. Vitamin B9 (folic acid)
Folic acid has shown to process the property in reduced risk of endothelial dysfunction(1457), CHD(1453) and CVD(1454)(1455), produced blood cells,(1456) secured cell division(1456), and growth(1456), improved antioxidant stasis(1458), lowered risk of diabetes(1459), etc,... Folic acid deficiency may induce risk of early onset of diabetes(1460), metabolic syndrome associated with increased risk for diabetes and cardiovascular disease(1460), depressed cell-mediated immunity(1461).

h. Vitamin B12 (various cobalamins; commonly cyanocobalamin or methylcobalamin in vitamin supplements)
Epidemiological studies suggestion that vitamin B12 exhibits anti insulin resistance(1465) and endothelial dysfunction(1465), depression(1468)(1469) effects, etc,... Deficiency of vitamin B12 induced risk of neurocognitive disorders(1462)(1463), and decline(1462), obesity and overweight(1464), altered lipid profile in the prediction of metabolic risk(1466), cardiovascular disease associated to hyperhomocysteinemia(1467).

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References
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