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Lao Guan Cao or Lao He Cao is also known as ord Granesbill Herbs. The acrid, bitter and
neutral herb has been used in TCM to treat rheumatoid arthritis, muscle spasm and numbness, impact injuries, colitis, diarrhea, etc., as it promotes circulation in the collaterals and circulation in the channels, etc., by enhancing the functions of liver, kidney and spleen channels.
1. 3 hydrolyzable
5. Gallic acid
1. Anti-hepatitis B virus
In the examination of the effect of the polyphenolic extract from Geranium carolinianum L. (PPGC) on HBV replication both in vitro and in vivo, found that in human, HBV-transfected liver cell line HepG(2) 2.2.15, PPGC effectively suppressed the secretion of the HBV antigens in a dose-dependent manner with IC(50) values of 46.85 microg/ml for HBsAg and 65.60 microg/ml for HBeAg at day 9. Consistent with the HBV antigen reduction, PPGC (100 microg/ml) also reduced HBV DNA level by 35.9%. In the duck hepatitis B virus (DHBV) infected ducks, after PPGC was dosed intragastricly (i.g.) once a day for 10 days, the plasma DHBV DNA level was reduced, with an ED(50) value of 47.54 mg/kg(1).
1. Do not use the herb in new born, children or if you are pregnant or breast feeding without first consult with your doctor or related field specialist
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