Wednesday, June 8, 2016

The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: Top 5 Anti inflammatory Foods

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovascular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).

The prevention and management


Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.

Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).

The Top 5 Anti inflammatory Foods

According to Medical University Innsbruck, the interactions between diet,immunity, and the microbiota, may be necessary for the develop food-based approaches to prevent or treat many diseases(285).
1. Garlic
Garlic (Allium sativum) is a species in the onion genus, belongings to family Amaryllidaceae, native to central Asia, used popularly in traditional and Chinese medicine to treat common cold and flu(306), digestive disorders(313), diabetes(322)(323)(324), therosclerosis,(325), cardiovascular diseases(326)(327), strengthen immunity(319) against irregular cell growth suach as tumors(314)(315)(316)(317)(318), bacterias(310)(311)(312), fungii(310)(311) and virus(320)(321), lower blood pressure(328)(329)(330) and cholesterol levels(310)(331), etc. Recent studies also showed that garlic exhibits its anti-inflammatory effects againstchronic inflammatory disease(307)(308)(309) through phytochemical allicin(307) and other machenisms(308)(309).

2. Ginger
Ginger (Zingiber officinale) or ginger root is the genus Zingiber, belongings to the family Zingiberaceae, native to Tamil, used in traditional and Chinese medicine to treat dyspepsia(332)(333), gastrointestinal disorder(334) such as nausea and vomiting(335), constipation(337), gastric ulcer(338),.... edema(339)(340), difficult urination(340), colic and diarrea(341), etc.... Strong evidences in Western studies also showed that ginger also induce some mechanisms for treatment of pschological symptoms, such as anxiety(342). depression(343),..., diabetes(344)(345), hypertension(346), irregular cell growth such as tumors(347)(348)(349), and rheumatoid arthritis(352) and osteoarthritis(336) through its anti inflammatory, antioxidant and immune-modulatory effects(346)(350)(351), speed up wounding healing(352)(353), etc.

3. Turmeric
Turmeric is a perennial plant in the genus Curcuma, belongings to the family Zingiberaceae, native to tropical South Asia. The herb has been used in traditional medicine as anti-oxidant(354)(355), hypoglycemic(356)(357), colorant(358), antiseptic(359)(360), wound healing(361) agents, and to treat flatulence(362), bloating(363), and appetite loss(364), ulcers(365), eczema(366), inflammations(367), etc. Epidemiological studies also found that the efficacy of turmeric for treatment for diabetes(369)(370), microbial infection(359)(371)(372), gastrointestinal diseases(359)(373) and irregular cell growth such as cancer(374)(375)(376) through its anti inflammatory(367)(368), antioxidant(377)(378) and immunmodulatory(379)(380) activities.

4. Green tea
Green tea contains more amount of antioxidants than any drinks or food with the same volume, and is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, green tea has been cultivated for commercial purposes all over the world. Epidemiological studies suggested that green tea consists many pharmateutical properties, including anti cancers(381)(382), anti diabetes(383)(384), induced weight loss(385)(386)anti aging and longevity(387)(388), anti allergy(389)(390), anti micro-organisms(391)(392), anti lipidemic(393)(394). anti stroke(385)(396) and cardiovascular diseases, through its antioxidant(397)(398), anti inflammatory(399)(400) and immune modulatory(401)(402) activities.

5. Shiitake mushrooms
Shiitake mushroom is an edible mushroom, genus Lentinula, belonging to familyMarasmiaceae, native to East Asia and widely cultivated for consumption for its health benefits and commercial purpose in many Asian countries. The herb has been used in traditional medicine as blood tonic agent and to strengthen immune system)403)(405), treat colds(407), measles(407), bronchial inflammations(407), etc. Recent studies showed that Shiitake mushrooms are also consisted properties of anti cancers(403)(404), anti microorganisms(407)(408) such as HIV)410)(411)and hepatitis virus(407)(412), enhanced immune system(403)(405)(406) against inflammation(413)(414) causes of chronic inflammatory diseases(415) and the development of free radicals(414)(416), lowering cholesterol levels(407)(417)(418), treating heart disease(407)(419), diabetes(407)(420), etc....

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References
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(381) Induction of apoptosis and cell cycle arrest in cancer cells by in vivo metabolites of teas by Zhang G1, Miura Y, Yagasaki K.(PubMed)
(382) Antimutagenic and anticarcinogenic activity of tea polyphenols by Kuroda Y1, Hara Y.(PubMed)
(383) High oolong tea consumption predicts future risk of diabetes among Japanese male workers: a prospective cohort study by Hayashino Y1, Fukuhara S, Okamura T, Tanaka T, Ueshima H; HIPOP-OHP Research Group.(PubMed)
(384) Antihyperglycemic effect of oolong tea in type 2 diabetes by Hosoda K1, Wang MF, Liao ML, Chuang CK, Iha M, Clevidence B, Yamamoto S.(PubMed)
(385) Beneficial effects of oolong tea consumption on diet-induced overweight and obese subjects by He RR1, Chen L, Lin BH, Matsui Y, Yao XS, Kurihara H.(PubMed)
(386) Thermogenic ingredients and body weight regulation by Hursel R1, Westerterp-Plantenga MS.(PubMed)
(387) Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity by Calabrese V1, Cornelius C, Cuzzocrea S, Iavicoli I, Rizzarelli E, Calabrese EJ.(PubMed)
(388) The potential influence of plant polyphenols on the aging process by Cherniack EP1.(PubMed)
(389) Antiallergic constituents from oolong tea stem by Ohmori Y1, Ito M, Kishi M, Mizutani H, Katada T, Konishi H.(PubMed)
(390) [Effect of tea extracts, catechin and caffeine against type-I allergic reaction].[Article in Japanese] by Shiozaki T1, Sugiyama K, Nakazato K, Takeo T.(PubMed)
(391) Antibacterial activity of Iranian green and black tea on streptococcus mutans: an in vitro study by Naderi NJ1, Niakan M, Kharazi Fard MJ, Zardi S.(PubMed)
(392) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas by Friedman M1.(PubMed)
(393) Mechanisms of hypolipidemic and anti-obesity effects of tea and tea polyphenols by Lin JK1, Lin-Shiau SY.(PubMed)
(394) Polyphenol-enriched oolong tea increases fecal lipid excretion by Hsu TF1, Kusumoto A, Abe K, Hosoda K, Kiso Y, Wang MF, Yamamoto S.(PubMed)
(395) Green and black tea consumption and risk of stroke: a meta-analysis by Arab L1, Liu W, Elashoff D.(PubMed)
(396) Does tea affect cardiovascular disease? A meta-analysis by Peters U1, Poole C, Arab L.(PubMed)
(397) Determination of tea components with antioxidant activity by Cabrera C1, Giménez R, López MC.(PubMed)
(398) Structural determination and DPPH radical-scavenging activity of two acylated flavonoid tetraglycosides in oolong tea (Camellia sinensis) by Lee VS1, Chen CR, Liao YW, Tzen JT, Chang CI.(PubMed)
(399) Evaluation of anti-inflammatory effects of green tea and black tea: A comparative in vitro study by Chatterjee P1, Chandra S, Dey P, Bhattacharya S.(PubMed)
(400) Anti-inflammatory and anti-oxidative effects of the green tea polyphenol epigallocatechin gallate in human corneal epithelial cells by Cavet ME1, Harrington KL, Vollmer TR, Ward KW, Zhang JZ.(PubMed)
(401) Immunomodulatory effects of EGCG fraction of green tea extract in innate and adaptive immunity via T regulatory cells in murine model by Kuo CL1, Chen TS, Liou SY, Hsieh CC.(PubMed)
(402) Immunomodulating effects of epigallocatechin-3-gallate from green tea: mechanisms and applications by Pae M1, Wu D.(PubMed)
(403) Structure and inducing tumor cell apoptosis activity of polysaccharides isolated from Lentinus edodes by Wang KP1, Zhang QL, Liu Y, Wang J, Cheng Y, Zhang Y.(PubMed)
(404) Polysaccharides from Tricholoma matsutake and Lentinus edodes enhance 5-fluorouracil-mediated H22 cell growth inhibition by Ren M, Ye L, Hao X, Ren Z, Ren S, Xu K, Li J.(PubMed)
(405) Structure and immuno-stimulating activities of a new heteropolysaccharide from Lentinula edodes by Xu X1, Yan H, Zhang X.(PubMed)
(406) Dietary supplementation with rice bran fermented with Lentinus edodes increases interferon-γ activity without causing adverse effects: a randomized, double-blind, placebo-controlled, parallel-group study by Choi JY, Paik DJ, Kwon DY, Park Y1.(PubMed)
(407) Lentinus edodes: a macrofungus with pharmacological activities by Bisen PS1, Baghel RK, Sanodiya BS, Thakur GS, Prasad GB.(PubMed)
(408) An examination of antibacterial and antifungal properties of constituents ofShiitake (Lentinula edodes) and oyster (Pleurotus ostreatus) mushrooms by Hearst R1, Nelson D, McCollum G, Millar BC, Maeda Y, Goldsmith CE, Rooney PJ, Loughrey A, Rao JR, Moore JE.(PubMed)
(409) Antimicrobial properties of shiitake mushrooms (Lentinula edodes) by Rao JR, Smyth TJ, Millar BC, Moore JE.(PubMed)
(410) A placebo-controlled trial of the immune modulator, lentinan, in HIV-positive patients: a phase I/II trial by Gordon M1, Bihari B, Goosby E, Gorter R, Greco M, Guralnik M, Mimura T, Rudinicki V, Wong R, Kaneko Y.(PubMed)
(411) A phase II controlled study of a combination of the immune modulator, lentinan, with didanosine (ddI) in HIV patients with CD4 cells of 200-500/mm3 by Gordon M1, Guralnik M, Kaneko Y, Mimura T, Goodgame J, DeMarzo C, Pierce D, Baker M, Lang W.(PubMed)
(412) [Liver protective effect of Lentinula edodes mycelia(LEM)].[Article in Japanese] by Yagi K1.(PubMed)
(413) Anti-inflammatory effects of five commercially available mushroom species determined in lipopolysaccharide and interferon-γ activated murine macrophages by Gunawardena D1, Bennett L, Shanmugam K, King K, Williams R, Zabaras D, Head R, Ooi L, Gyengesi E, Münch G.(PubMed)
(414) Effect of shiitake (Lentinus edodes) extract on antioxidant and inflammatory response to prolonged eccentric exercise by Zembron-Lacny A1, Gajewski M, Naczk M, Siatkowski I.(PubMed)
(415) Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment by Martin KR1.(PubMed)
(416) Fumigation with essential oils improves sensory quality and enhancedantioxidant ability of shiitake mushroom (Lentinus edodes) by Jiang T1, Luo Z2, Ying T3.(PubMed)
(417) Antihyperlipidemic Effect of Dietary Lentinus edodes on Plasma, Feces and Hepatic Tissues in Hypercholesterolemic Rats by Yoon KN1, Alam N, Lee JS, Cho HJ, Kim HY, Shim MJ, Lee MW, Lee TS.(PubMed)
(418) Cholesterol-lowering effects of maitake (Grifola frondosa) fiber, shiitake(Lentinus edodes) fiber, and enokitake (Flammulina velutipes) fiber in rats by Fukushima M1, Ohashi T, Fujiwara Y, Sonoyama K, Nakano M.(PubMed)
(419) Effects of Lentinus edodes mycelia on dietary-induced atherosclerotic involvement in rabbit aorta by Yamada T1, Oinuma T, Niihashi M, Mitsumata M, Fujioka T, Hasegawa K, Nagaoka H, Itakura H.(PubMed)
(420) Protective effects of fractional extracts from Panellus serotinus on non-alcoholic fatty liver disease in obese, diabetic db/db mice by Inafuku M1, Nagao K, Nomura S, Shirouchi B, Inoue N, Nagamori N, Nakayama H, Toda T, Yanagita T.(PubMed)

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