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Wednesday, July 13, 2016

Most Common Diseases of 50plus: Thyroid disease: Hypothyroidism – Treatments In conventional medicine perspective

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                         Thyroid disease


Thyroid disease is defined as a condition of malfunction of thyroid. Hyperthyroidism is a condition in which the thyroid gland is over active and produces too much thyroid hormones.



                       Hypothyroidism


Hypothyroidism is a condition in which the thyroid gland is under active and produces very little thyroid hormones.

                       The Treatments

 In conventional medicine perspective
Patients with hypothyroidism are treated by Thyroid hormone therapy with doses depending to the stage and types of the diseases

In patients with overt hypothyroidism defined as low FT4 and elevated TSH or TSH > 10 mU/L a replacement with levothyroxine is clearly indicated. In patients with subclinical hypothyroidism defined as a TSH between 4 and 10 mU/L and normal FT4, the treatment with Levothyroxine depends on the underlying disease and symptoms. Levothyroxine is a prohormone with is activated by deiodination in the organs to triiodothyronine, according to the study by Medizinische Klinik IV der Universität München(52a).

Standard therapy for patients with primary hypothyroidism is replacement with synthetic thyroxine, which undergoes peripheral conversion to triiodothyronine, the active form of thyroid hormone. According to the study by the University College Dublin, in a randomized, double-blind, placebo-controlled trial conducted from May 2000 to February 2002 at a military treatment facility that serves active duty and retired military personnel and their family members, indicated that compared withlevothyroxine alone, treatment of primary hypothyroidism with combinationlevothyroxine plus liothyronine demonstrated no beneficial changes in body weight, serum lipid levels, hypothyroid symptoms as measured by a HRQL questionnaire, and standard measures of cognitive performance(53). Other in the study to examine the efficacy of combination therapy with levothyroxine and liothyronine in improvement of general health, psychological problems, and metabolic status in primary hypothyroidism, showed that Psychosocial scores, body weight, heart rate, blood pressure, and lipid profile in the two groups remained constant(54).

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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/17933284
(52a) http://www.ncbi.nlm.nih.gov/pubmed/23801264
(53) http://www.ncbi.nlm.nih.gov/pubmed/14665656
(54) http://www.ncbi.nlm.nih.gov/pubmed/19701833                         


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