Friday, July 15, 2016

The Smoothie of Cantaloupe and Juar tea for Prevention and Treatment of Skeletal Abnormalities in Conorenal syndrome

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie at least prolong and prevention of Skeletal Abnormalities in Conorenal syndrome 
Yield: 2 servings (about 8 ounces each)

1 1/2 cup cantaloupe
1 cup of Juar tea

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of Skeletal Abnormalities in Conorenal syndrome has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Recent studies back by well known institutions proposed, cantaloupe and Juar tea may be the next generation of natural ingredients for prevention and treatment of Skeletal Abnormalities in Conorenal syndrome.

Conorenal syndrome, also known as Mainzer-Saldino syndrome or Saldino-Mainzer disease is a medical condition of diseases involved kidney, skeletal system and eye with the same genetic mutation.
Skeletal Abnormalities in Conorenal syndrome is a condition of bone abnormalities observed in multiple bones as well as inducing craniosynostosis, the short stature.

 Cantaloupe is a species in the family Cucurbitaceae, originally cultivated by the Egytian (The European cantaloupe) and by India and Africa (The North American cantaloupe).

Antioxidant enzyme extracellular superoxide dismutase (EC-SOD),commercially obtained from cantaloupe and in regulation of ROS-mediated tissue damage(1) plays an important antioxidant defense function in skeletal muscle against cardiac cachexia and exercise intolerance in congestive heart failure(CHF)(2).
According to the study led by the University of Virginia, the antioxidant enzyme also enhanced by exercise training in expression of skeletal muscle and elicitation of positive health outcomes in individuals through ameliorated oxidative stress(3).

Juar tea, type of black tea native to African,  according to the National Defense Medical College, Saitama, Japan, Consumption of polyphenol-rich juar tea increases endothelium-bound extracellular superoxide dismutase levels (EC-SOD) of that may be beneficiary to patient with Conorenal syndrome induced skeletal Abnormalities(4)(5).

The effectiveness of   Cantaloupe and Juar tea  may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for reduced risk, complications and treatment of Skeletal Abnormalities in Conorenal syndrome with little or no adverse effects.

People who are at high risk of Skeletal Abnormalities in Conorenal syndrome due to mutation gene should drink no more than 4 servings daily, depending to digestive toleration.

Life style and diet pattern change are necessary.

(1) Extracellular superoxide dismutase in biology and medicine by Fattman CL1, Schaefer LM, Oury TD.(PubMed)
(2) Extracellular superoxide dismutase ameliorates skeletal muscle abnormalities, cachexia, and exercise intolerance in mice with congestive heart failure by Okutsu M1, Call JA1, Lira VA1, Zhang M1, Donet JA1, French BA1, Martin KS1, Peirce-Cottler SM1, Rembold CM1, Annex BH1, Yan Z2.(PubMed)
(3) Enhanced skeletal muscle expression of extracellular superoxide dismutase mitigates streptozotocin-induced diabetic cardiomyopathy by reducing oxidative stress and aberrant cell signaling. by Call JA1, Chain KH1, Martin KS1, Lira VA1, Okutsu M1, Zhang M1, Yan Z2.(PubMed)
(4) Consumption of polyphenol-rich juar tea increases endothelium-bound extracellular superoxide dismutase levels in men with metabolic syndrome: link with LDL oxidizability by Uto-Kondo H1, Ayaori M, Kishimoto Y, Adachi T, Takiguchi S, Yakushiji E, Sasaki M, Komatsu T, Kondo K, Ikewaki K.(PubMed)
(5) Superoxide Dismutase supplement pill SOD benefit and risk, by Ray Sahelian, M.D

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