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Han Lian Cao is also known as Yerbadetajo Herb. The sweet, sour and slightly cold herb has been used in TCM as immune enhancer and to treat nose bleeding, blood in urine, diarrhea with blood, excessive bleeding during menopause, etc., as it nourishes Yin, benefits the Kidneys, cools Blood, stops bleeding, etc., by enhancing the functions of liver and kidney channels.
1. Anti malaria
In the evaluation of the adulticidal activity and adult emergence inhibition (EI) of leaf hexane, chloroform, ethyl acetate, acetone, and methanol extracts of Aegle marmelos (Linn.) Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wall. ex Nees., Cocculus hirsutus L. Diels, Eclipta prostrata L., and Tagetes erecta L. tested against malarial vector, found that all plant extracts showed moderate adulticidal activity and EI effects after 24 h of exposure at 1,000 ppm; however, the highest adulticidal activity was observed in ethyl acetate extract of A.lineata, chloroform extract of A. paniculata, acetone extract of C. hirsutus, and methanol extract of T. erecta (LD(50) = 126.92, 95.82, 109.40, and 89.83 ppm, according to “Efficacy of medicinal plant extracts against malarial vector, Anopheles subpictus Grassi” by Elango G, Rahuman AA, Kamaraj C, Bagavan A, Zahir AA.(1).
2. Anti parasites
In the investigation of the antiparasitic activities in determination of the efficacies of leaf hexane, chloroform, ethyl acetate, acetone and methanol extracts of Aegle marmelos (Linn.) Correa ex Roxb, Andrographis lineata Wallich ex Nees., Andrographis paniculata (Burm.f.) Wallich ex Nees., Cocculus hirsutus (L.) Diels, Eclipta prostrata L., and Tagetes erecta L. against the adult cattle tick Haemaphysalis bispinosa Neumann 1897 (Acarina: Ixodidae), indicated that the highest parasitic activity was found in leaf ethyl acetate extract of A. lineata, methanol extract of A. marmelos, A. paniculata, and C. hirsutus against H. bispinosa (LC(50) = 395.27, 358.45, 327.21 and 420.50 ppm); ethyl acetate extract of A. paniculata, C. hirsutus, methanol extracts of A. marmelos, A. lineata, and E. prostrata against the larvae of R. microplus (LC(50) = 207.70, 258.61, 134.09, 206.00, and 274.33 ppm); hexane extract of A. lineata, ethyl acetate extract of A. paniculata, E. prostrata, acetone extracts of T. erecta, methanol extracts of A. marmelos and C. hirsutus against P. cervi (LC(50) = 254.23, 451.17, 425.73, 253.60, 542.71, and 360.17 ppm), respectively, according to “Evaluation of medicinal plant extracts against ticks and fluke” by Elango G, Rahuman AA.(2).
3. Abtioxidants activity
In the elucidation of the biological basis for hypolipidemic and antioxidant activities of E. prostrata, indicated that the results clearly demonstrate the effects of E. prostrata on serum lipid and oxidative metabolism in rats. The health-promoting effects of E. prostrata, which were demonstrated in this study in a rat model, may have implications for atherosclerosis and hypercholesterolemia in humans, according to ‘The butanol fraction of Eclipta prostrata (Linn) effectively reduces serum lipid levels and improves antioxidant activities in CD rats” by Kim DI, Lee SH, Choi JH, Lillehoj HS, Yu MH, Lee GS.(3).
1. Do not use the herb in case of spleen deficiency with digestive problem
2. Do not use the herb in newborn, children or if you are pregnant or breast feeding without consulting first with the related field specialist.
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