Saturday, June 4, 2016

Most common Diseases of 50plus: The Obesity' Article of Antioxidant Melatonin and Non alcoholic fatty liver disease

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Obesity is a medical condition of excess body fat accumulated overtime, while overweight is a condition of excess body weight relatively to the height. According to the Body Mass Index(BMI), a BMI between 25 to 29.9 is considered over weight, while a BMI of over 30 is an indication of obesity. According to the statistic, 68% of American population are either overweight or obese.

You can calculate your BMI index BMI= weight (kg)/ height (m2)

 The Obesity' Article of Antioxidant Melatonin and Non alcoholic fatty liver disease

Melatonin supplement, a synthetic product of the vertebrate pineal gland was sfound to have significantly broader actions including oncostatic effects (Blask et al., 2002), immunesystem stimulation (Guerrero & Reiter, 2002)and anti-inflammatory functions.
Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.

The benefits
In the study to investigate melatonin's preventive action in oxidative stress in a rat model with high fat diet-induced non-alcoholic fatty liver disease (NAFLD), Melatonin was ineffective in reverse the abnormal action of lipid accumulation and in enhancing normal lipidemic serum markers, but it enhanced the antioxidant effects by protecting the liver against the peroxidation and oxidative stress in liver tissue as well as a significant increasing of glutathione.

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The side effects of Melatonin may include nightmares, nausea, abdominal issues, an altered sleep pattern, etc.

(1) Melatonin as an antioxidant: biochemical mechanisms andpathophysiological implications in humans (Acta, Biochimica, Polonica)
(2) Melatonin attenuates high fat diet-induced fatty liver disease in rats by Hatzis G, Ziakas P, Kavantzas N, Triantafyllou A, Sigalas P, Andreadou I, Ioannidis K, Chatzis S, Filis K, Papalampros A, Sigala F.(PubMed)

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