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Bai Lian is also known as Japanese Ampelopsis Root, the bitter, sweet, acrid and cool herb has been used in TCM to redice infection and to treat carbuncles, sores, scalding injuries, dysentery with blood, intestine pain, hemorrhoids as it clears Heat, expels toxins, resolves ulcers, promotes muscle regeneration, etc, by promoting the function of liver channel.
2. Carbolic acid
3. Campholic acid
4. 24-ethyl sterol
6. Fatty acid
1. Skin whiteners
Extract from Ampelopsis japonica, Lindera aggregata, Qian-wang-hong-bai-san, or San-bai-tang has exerted the activity against murine tyrosinase, that can eads to the development of skin whiteners, according to the study of “Screening of Chinese herbal medicines for antityrosinase activity in a cell free system and B16 cells” by Ye Y, Chou GX, Mu DD, Wang H, Chu JH, Leung AK, Fong WF, Yu ZL.(1).
2. Promyelocytic leukemia (HL-60) cells.
Momordin I, a compound purified from a plant, Ampelopsis japonica, induced apoptosis of HL-60 cells by reduction of the Bcl-2:Bax ratio and by activation of caspase-3, according to the study of “Induction of apoptosis by momordin I in promyelocytic leukemia (HL-60) cells” by Kim JH, Ju EM, Lee DK, Hwang HJ.(2).
Momordin I, extract from Bai Lian has shown the activity of suppressing osteoclastogenesi by targeting IkappaB degradation and c-Fos expression, according to the study of “Momordin I, an inhibitor of AP-1, suppressed osteoclastogenesis through inhibition of NF-kappaB and AP-1 and also reduced osteoclast activity and survival” by Hwang YH, Lee JW, Hahm ER, Jung KC, Lee JH, Park CH, Rhee HS, Ryu JM, Kim HK, Yang CH.(3).
4. Colon CancerMethanol extract of Ampelopsis radix showed measurable anticancer activity against murine colon cancer by reducing the weight rate of 17.73% at 90 mg/kg dose, according to the study of “Momordins inhibit both AP-1 function and cell proliferation” by Lee DK, Kim B, Lee SG, Gwon HJ, Moon EY, Hwang HS, Seong SK, Lee M, Lim MJ, Sung HJ, Shin DH, Yoon SJ, Yang CH.(4).
In a study of 140 patient with acute and chronic infection type of diarrhea with the use of powder of bai lian in capsules with 0.3 g per capsule, 6 capsules, 3 times per day has effectively rate of 96.55% and 91.66%, according to the article of “Bai lian” by Joe Hing kwok Chu(5).
1. No side effect is know, if not overdosed
2. Do not use the herb if you are pregnant without approval of the related field specialist.
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