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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Polycystic Ovarian Syndrome
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasingaltered glucose tolerance(20), CVD and hypertension(21).
The prevention and management
Polycystic ovary syndrome (PCOS) is unpreventable in Western medicine. Early diagnosis and treatment may reduce risk of its complications, including infertility, metabolic syndrome, obesity, diabetes, cardiovascular diseases, stroke, etc.
The General Approaches to prevent the unpreventable?
Although PCOS cannot be completely avoided, strengthening immunity has shown a significant reduction of chronic inflammatory diseases(266)(267)(268).
1. Healthy lifestyle(256)(257)(258)
According to Shahid Beheshti University of Medical Sciences, women with unhealthy life style are associated to increased risk of chronic diseases(260), including PCOs in comparison to those of healthy women(259), probably due to nutrient deficiency effects of immune functioning(261).
2. Balanced diet
Epidemiological data suggest that dietary patterns strongly affect inflammatoryprocesses(265).
Balancing diet(257)(258) with high in veggies and fruits(257) and less in meats not only provides sufficient nutrients to your body but also enhances the immunity in fighting against inflammatory diseases(264), including PCOs(264), irregular cell growth(263) and oxidative stress(262). Reduced intake of trans and saturated fats and increased intake of omega-3 and omega-9 fatty acids(257) and eating anti-inflammatory foods (fiber(272)(273), omega-3 fatty acids(269), vitamin E(270), and red wine(271) should also be emphasized(255)(265).
3. Moderate exercise(257)
Moderate exercise not only increases blood flow to strengthen the body tissues(274)(275) and organs(276), including the reproductive system but also enhances the immunity(277) in fighting against inflammatory process(277)(278) due to irregular cell growth(281)(282) and foreign invasion(279)(280).
Yoga is a physical, mental, and spiritual practice in Hinduism, Buddhism.
According to studies holistic yoga therapy showed a significant effects in reducing anti-müllerian hormone (AMH-primary outcome), luteinizing hormone (LH), testosterone, hirsutism, and improving menstrual frequency, glucose, lipid, and insulin values(284) with nonsignificant changes in body weight, FSH, and prolactin in adolescent PCOS(283).
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(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndromeand healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R1, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N1, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO1, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK1, Katalenich B2, Nagireddy P3, Chabbra P4, Kuhadiya N5, Fonseca V1.(PubMed)
(14) Acne in hirsute women by Lumezi BG1, Pupovci HL1, Berisha VL1, Goçi AU2, Gerqari A3.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N1, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H1, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA1, Azizia MM1, Hardiman PJ2.(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M1, Kjaer SK2, Jensen A1, Munk C1, Mellemkjaer L3.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(260) The Science of Stress, Bad Habits, and Risk of Chronic Diseases
(261) The risks of poor nutrition(SA health)
(262) Circulating markers of oxidative stress and polycystic ovary syndrome (PCOS): a systematic review and meta-analysis by Murri M1, Luque-Ramírez M, Insenser M, Ojeda-Ojeda M, Escobar-Morreale HF.(PubMed)
(263) The reproductive phenotype in polycystic ovary syndrome by Chang RJ1.(PubMed)
(264) Mesenchymal stem/progenitors and other endometrial cell types from women with polycystic ovary syndrome (PCOS) display inflammatory and oncogenic potential by Piltonen TT1, Chen J, Erikson DW, Spitzer TL, Barragan F, Rabban JT, Huddleston H, Irwin JC, Giudice LC.(PubMed)
(265) Anti-inflammatory effects of plant-based foods and of their constituents by Watzl B1.(PubMed)
(266) [Immunopathological responses in women with chronic inflammatorydiseases of the uterus and appendages and their therapeutic correction].[Article in Russian] by Medvedev BI1, Kazachkova EA, Kazachkov EL.(PubMed)
(267) Cross Talk Between ER Stress, Oxidative Stress, and Inflammation in Health and Disease by Dandekar A1, Mendez R, Zhang K.(PubMed)
(268) New dog and new tricks: evolving roles for IL-33 in type 2 immunity by Lott JM1, Sumpter TL1, Turnquist HR2.(PubMed)
(269) Dietary n-6 and n-3 fatty acids in immunity and autoimmune disease by Harbige LS1.(PubMed)
(270) Effect of conjugated linoleic Acid, vitamin e, alone or combined on immunityand inflammatory parameters in adults with active rheumatoid arthritis: a randomized controlled trial by Aryaeian N1, Djalali M2, Shahram F3, Djazayery A4, Eshragian MR5.(PubMed)
(271) Red wine may be used in the therapy of myocarditis by Chen CJ1, Yu W, Wang W.(PubMed)
(272) High dietary fiber lowers systemic inflammation: potential utility in COPD and lung cancer by Young RP1, Hopkins RJ2.(PubMed)
(273) Dietary fibre linked to decreased inflammation in overweight minority youth by Miller SJ1, Batra AK, Shearrer GE, House BT, Cook LT, Pont SJ, Goran MI, Davis JN.(PubMed)
(274) Effects of high-intensity blood flow restriction exercise on muscle fatigue by Neto GR1, Santos HH2, Sousa JB3, Júnior AT4,(PubMed)
(275) Influence of Blood Flow Restriction During Low-intensity Resistance Exercise on the Post-exercise Hypotensive Response by Maior AS1, Simão R, Rocha Martins MS, Freitas de Salles B, Willardson JM. Araújo JP3, Aniceto RR5, Sousa MS3.(PubMed)
(276) Impact of exercise on muscle and nonmuscle organs by Boström PA1, Graham EL, Georgiadi A, Ma X.(PubMed)
(277) Exercise as an anti-inflammatory therapy for rheumatic diseases-myokine regulation by Benatti FB1, Pedersen BK2.(PubMed)
(278) The role of exercise-induced myokines in muscle homeostasis and the defense against chronic diseases by Brandt C1, Pedersen BK.(PubMed)
(279) Enhanced follicular dendritic cell-B cell interaction in HIV and SIV infections and its potential role in polyclonal B cell activation by Rosenberg YJ1, Lewis MG, Kosco-Vilbois MH.(PubMed)
(280) THE FATE OF THE GIANT CELLS IN HEALING TUBERCULOUS TISSUE, AS OBSERVED IN A CASE OF HEALING TUBERCULOUS MENINGITIS by Hektoen L1.(PubMed)
(281) Cell-mediated immunity to mouse tumors: some recent findings. Hellström KE, Hellström I.(PubMed)
(282) Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors by Ngiow SF1, von Scheidt B, Akiba H, Yagita H, Teng MW, Smyth MJ.(PubMed)
(283) Effects of a holistic yoga program on endocrine parameters in adolescents with polycystic ovarian syndrome: a randomized controlled trial by Nidhi R1, Padmalatha V, Nagarathna R, Amritanshu R.(PubMed)
(284) Effect of a yoga program on glucose metabolism and blood lipid levels in adolescent girls with polycystic ovary syndrome byNidhi R1, Padmalatha V, Nagarathna R, Ram A.(PubMed)
(285) Food, Immunity, and the Microbiome by Tilg H1, Moschen AR2.(PubMed)