A recent study suggested that Aloe Vera may process an anti-constipation effect, through the expression of improved intestinal motility, increased fecal volume and normalized body weight.
Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has become very popular for commercial cultivation due to its health benefits. Aloe Vera has been used in herbal medicine in treating many kinds of diseases, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc.
Constipation is a condition in difficulty in emptying the bowels, in the most case associated with hardened feces.
According to the University of Fort Hare, in a constipation condition induced by oral administration of loperamide (3 mg/kg body weight) in comparison to control rats received normal saline, intake of aqueous leaf extract of Aloe ferox Mill. with 50, 100 and 200 mg/kg body weight/day or 7 days improved the laxative property with the best efficacy in 200 mg/kg body weight.
Dr. Wintola OA, the lead researcher said, "The effect of the extract compares favorably well with senokot, a standard laxative drug. These findings have, therefore, lent scientific credence to the folkloric use of the herb as a laxative agent.."
In addition to the above, also in loperamide-induced constipated rats, intake of aqueous extract of Aloe ferox Mill. showed no toxicity to the kidney and liver even with of highest doses of 200 mg/kg bodyweight for 7 days. The study also insisted that extract is very effective in compared favorably with senokot, a recommended drug for the treatment of constipation.
Taking together, even though living with constipation is an irritable and uncomfortable experience but the use of herbal medicine in the treatment of constipation should be taken with care. People should start with small doses and increase the amount gradually.
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Sources
(1) The effect of Aloe ferox Mill. in the treatment of loperamide-induced constipationin Wistar rats by Wintola OA1, Sunmonu TO, Afolayan AJ.(PubMed)
(2) A qualitative study of quality of life and the experience of complementary and alternative medicine in Korean women with constipation by Lee EJ1, Warden S.(PubMed)
(3) Toxicological evaluation of aqueous extract of Aloe ferox Mill. in loperamide-induced constipated rats by Wintola OA1, Sunmonu TO, Afolayan AJ.(PubMed)
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