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Saturday, June 25, 2016

Most Common Disease of 50+: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs) - Diseases associated with Gout -Hyperuricemia

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. A community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home. Musculoskeletal pain was reported by 57% of those interviewed(1).

Types of Musculo-Skeletal disorders in elder(2)
1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia


                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.


                     Diseases associated with Gout


According to the UK Gout Society, diseases associated to gout may include
5. Hyperuricemia

Hyperuricemia, a condition with over expression of uric acid in the blood through liver most often found in patients with gout. According to Dr. Li YM. said, "It has been widely accepted that the increase in the level of uric acid significantly raises the risks of gout, cardiovascular disease, and type 2 diabetes."
It is acceptance epidemiological studies that high fruit and soybean products dietary intervention could be an effective alternative to a standard diet for achieving clinically important reductions in SUA for asymptomatic hyperuricemia patients(61). And major dietary patterns such as animal products and fried food are associated to risk of hyperuricemia(62).
According to the Chiang Mai University, green tea extract (GTE) also promoted hypouricemic and anti gout effects through modestly lowering serum uric acid (SUA) level and decreasing uric acid clearance(63).
Reduced intake of food with rich purine, alcohol intake as well as controlling obesity and blood pressure, improving the status of lipid metabolic disorder together with programs as hypertension control etc.(64).

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References
(61) Comparison of the effect of high fruit and soybean products diet and standard diet interventions on serum uric acid in asymptomatic hyperuricemia adults: an open randomized controlled trial BY Zhang M1, Gao Y2, Wang X1, Liu W3, Zhang Y3, Huang G1.(PubMed)
(62) Major dietary patterns and risk of asymptomatic hyperuricemia in Chinese adults by Zhang M1, Chang H, Gao Y, Wang X, Xu W, Liu D, Li G, Huang G.(PubMed)
(63) Effects of green tea extract on serum uric acid and urate clearance in healthy individuals by Jatuworapruk K1, Srichairatanakool S, Ounjaijean S, Kasitanon N, Wangkaew S, Louthrenoo W.(PubMed)
(64) [Epidemiological study on hyperuricemia and gout in Foshan areas, Guangdong province.][Article in Chinese] by Yu JW1, Yang TG, Diao WX, Cai XQ, Li T, Zhong H, Hu DL, Chen CQ, Chen ZX.(PubMed)

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